Basal Cell Carcinoma Arising within Seborrheic Keratosis
Malignant tumour development within a seborrheic keratosis (SK) is extremely rare. Though the most commonly developed malignant tumour is the basal cell carcinoma (BCC), other tumour types have also been reported in literature. Herein, we will report a superficial type BCC case developed within SK...
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| Format: | Article |
| Language: | English |
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JCDR Research and Publications Private Limited
2014-07-01
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| Series: | Journal of Clinical and Diagnostic Research |
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| Online Access: | https://jcdr.net/articles/PDF/4604/8665_CE%20and%20PPF1(AG)_F(San)_PFA(AK)_PF2(AGAK).pdf |
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| author | Recep Bedir Cüneyt Yurdakul Hasan Güçer Ibrahim Şehitoğlu |
| author_facet | Recep Bedir Cüneyt Yurdakul Hasan Güçer Ibrahim Şehitoğlu |
| author_sort | Recep Bedir |
| collection | DOAJ |
| description | Malignant tumour development within a seborrheic keratosis (SK) is extremely rare. Though the most commonly developed malignant
tumour is the basal cell carcinoma (BCC), other tumour types have also been reported in literature. Herein, we will report a superficial type
BCC case developed within SK localized in hairy skin of a 78-year-old female patient. In immunohistochemical evaluation, diffuse positive
staining with CK19 and over-expression in p53 compared with non-neoplastic areas were determined in neoplastic basaloid islands.
It is always not easy to differentiate especially superficial type BCC cases from non-neoplastic epithelium of SK with histopathological
evaluation. As far as this reason we believe that in difficult differentiation of these 2 lesions, in order to show the differentiation in basal
epithelium, immunohistochemical evaluation may be helpful. |
| first_indexed | 2024-12-12T05:44:33Z |
| format | Article |
| id | doaj.art-1c4fa98f7f3e430eba62c2ea64786bce |
| institution | Directory Open Access Journal |
| issn | 2249-782X 0973-709X |
| language | English |
| last_indexed | 2024-12-12T05:44:33Z |
| publishDate | 2014-07-01 |
| publisher | JCDR Research and Publications Private Limited |
| record_format | Article |
| series | Journal of Clinical and Diagnostic Research |
| spelling | doaj.art-1c4fa98f7f3e430eba62c2ea64786bce2022-12-22T00:35:49ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2014-07-0187YD06YD0710.7860/JCDR/2014/8665.4604Basal Cell Carcinoma Arising within Seborrheic KeratosisRecep Bedir0Cüneyt Yurdakul1Hasan Güçer2Ibrahim Şehitoğlu3Medical Faculty, Department of Pathology, Recep Tayyip Erdogan University, Rize, Turkey.Medical Faculty, Department of Pathology, Recep Tayyip Erdogan University, Rize, Turkey.Medical Faculty, Department of Pathology, Recep Tayyip Erdogan University, Rize, Turkey.Medical Faculty, Department of Pathology, Recep Tayyip Erdogan University, Rize, Turkey.Malignant tumour development within a seborrheic keratosis (SK) is extremely rare. Though the most commonly developed malignant tumour is the basal cell carcinoma (BCC), other tumour types have also been reported in literature. Herein, we will report a superficial type BCC case developed within SK localized in hairy skin of a 78-year-old female patient. In immunohistochemical evaluation, diffuse positive staining with CK19 and over-expression in p53 compared with non-neoplastic areas were determined in neoplastic basaloid islands. It is always not easy to differentiate especially superficial type BCC cases from non-neoplastic epithelium of SK with histopathological evaluation. As far as this reason we believe that in difficult differentiation of these 2 lesions, in order to show the differentiation in basal epithelium, immunohistochemical evaluation may be helpful.https://jcdr.net/articles/PDF/4604/8665_CE%20and%20PPF1(AG)_F(San)_PFA(AK)_PF2(AGAK).pdfimmunohistochemistryseborrheic keratosisskin cancer |
| spellingShingle | Recep Bedir Cüneyt Yurdakul Hasan Güçer Ibrahim Şehitoğlu Basal Cell Carcinoma Arising within Seborrheic Keratosis Journal of Clinical and Diagnostic Research immunohistochemistry seborrheic keratosis skin cancer |
| title | Basal Cell Carcinoma Arising within Seborrheic Keratosis |
| title_full | Basal Cell Carcinoma Arising within Seborrheic Keratosis |
| title_fullStr | Basal Cell Carcinoma Arising within Seborrheic Keratosis |
| title_full_unstemmed | Basal Cell Carcinoma Arising within Seborrheic Keratosis |
| title_short | Basal Cell Carcinoma Arising within Seborrheic Keratosis |
| title_sort | basal cell carcinoma arising within seborrheic keratosis |
| topic | immunohistochemistry seborrheic keratosis skin cancer |
| url | https://jcdr.net/articles/PDF/4604/8665_CE%20and%20PPF1(AG)_F(San)_PFA(AK)_PF2(AGAK).pdf |
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