Acute Hemorrhagic Edema following COVID-19 Infection

Background: Acute hemorrhagic edema of infancy (AHEI) is an immune complex-mediated leukocytoclastic vasculitis. Despite its worrisome appearance, it has a benign disease course with rare systemic involvement. Clinical Description: A 25-month-old male patient was brought to the pediatric outpatient...

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Main Authors: Cansu Kaymakci, Yasar Kandur
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2022-01-01
Series:Indian Pediatrics Case Reports
Subjects:
Online Access:http://www.ipcares.org/article.asp?issn=2772-5170;year=2022;volume=2;issue=4;spage=241;epage=244;aulast=Kaymakci
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author Cansu Kaymakci
Yasar Kandur
author_facet Cansu Kaymakci
Yasar Kandur
author_sort Cansu Kaymakci
collection DOAJ
description Background: Acute hemorrhagic edema of infancy (AHEI) is an immune complex-mediated leukocytoclastic vasculitis. Despite its worrisome appearance, it has a benign disease course with rare systemic involvement. Clinical Description: A 25-month-old male patient was brought to the pediatric outpatient clinic with a pink oval-shaped plaque-like rash all over the body and edema on the lower extremities and left auricle. The child was diagnosed as a case of coronavirus disease 2019 (COVID-19) 5 days before the present complaints. History and physical examination were otherwise unremarkable. Because of the patient's age, the purpuric appearance of lesions, distribution pattern of the rashes, localized edema, and no end-organ involvement, a possibility of AHEI, triggered by COVID-19, was considered and the patient was evaluated for the same. Management and Conclusions: The patient recovered in 15 days with no end-organ involvement. He was advised to continue regular follow-ups to look for long-term complications. AHEI is a benign condition which may occur in children following COVID-19 infection. It is essential to recognize the condition to avoid unnecessary investigations and treatment.
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spelling doaj.art-1c59d2085cc543478bcbdceaf501ac722024-03-25T15:39:08ZengWolters Kluwer Medknow PublicationsIndian Pediatrics Case Reports2772-51702772-51892022-01-012424124410.4103/ipcares.ipcares_212_22Acute Hemorrhagic Edema following COVID-19 InfectionCansu KaymakciYasar KandurBackground: Acute hemorrhagic edema of infancy (AHEI) is an immune complex-mediated leukocytoclastic vasculitis. Despite its worrisome appearance, it has a benign disease course with rare systemic involvement. Clinical Description: A 25-month-old male patient was brought to the pediatric outpatient clinic with a pink oval-shaped plaque-like rash all over the body and edema on the lower extremities and left auricle. The child was diagnosed as a case of coronavirus disease 2019 (COVID-19) 5 days before the present complaints. History and physical examination were otherwise unremarkable. Because of the patient's age, the purpuric appearance of lesions, distribution pattern of the rashes, localized edema, and no end-organ involvement, a possibility of AHEI, triggered by COVID-19, was considered and the patient was evaluated for the same. Management and Conclusions: The patient recovered in 15 days with no end-organ involvement. He was advised to continue regular follow-ups to look for long-term complications. AHEI is a benign condition which may occur in children following COVID-19 infection. It is essential to recognize the condition to avoid unnecessary investigations and treatment.http://www.ipcares.org/article.asp?issn=2772-5170;year=2022;volume=2;issue=4;spage=241;epage=244;aulast=Kaymakcicoronavirus disease 2019immune-complexleukocytoclastic vasculitispurpura
spellingShingle Cansu Kaymakci
Yasar Kandur
Acute Hemorrhagic Edema following COVID-19 Infection
Indian Pediatrics Case Reports
coronavirus disease 2019
immune-complex
leukocytoclastic vasculitis
purpura
title Acute Hemorrhagic Edema following COVID-19 Infection
title_full Acute Hemorrhagic Edema following COVID-19 Infection
title_fullStr Acute Hemorrhagic Edema following COVID-19 Infection
title_full_unstemmed Acute Hemorrhagic Edema following COVID-19 Infection
title_short Acute Hemorrhagic Edema following COVID-19 Infection
title_sort acute hemorrhagic edema following covid 19 infection
topic coronavirus disease 2019
immune-complex
leukocytoclastic vasculitis
purpura
url http://www.ipcares.org/article.asp?issn=2772-5170;year=2022;volume=2;issue=4;spage=241;epage=244;aulast=Kaymakci
work_keys_str_mv AT cansukaymakci acutehemorrhagicedemafollowingcovid19infection
AT yasarkandur acutehemorrhagicedemafollowingcovid19infection