Regulatory peculiar features of uncontrolled bronchial asthma

Bronchial asthma (BA) is a multifactorial disease which develops under the influence environmental factors in the presence of individual’s genetic predisposition. The mechanisms associated with the respiratory system dominate in its pathogenesis. The objective: to determine the regulatory features o...

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Main Authors: O. P. Romanchuk, Ya. I. Bazhora
Format: Article
Language:English
Published: Kazimierz Wielki University 2018-01-01
Series:Journal of Education, Health and Sport
Subjects:
Online Access:https://apcz.umk.pl/JEHS/article/view/25204
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author O. P. Romanchuk
Ya. I. Bazhora
author_facet O. P. Romanchuk
Ya. I. Bazhora
author_sort O. P. Romanchuk
collection DOAJ
description Bronchial asthma (BA) is a multifactorial disease which develops under the influence environmental factors in the presence of individual’s genetic predisposition. The mechanisms associated with the respiratory system dominate in its pathogenesis. The objective: to determine the regulatory features of the uncontrolled course of asthma. The results obtained. At the outpatient stage of treatment 71 male and female patients, mean age 41.0 ± 0.8 have been examined with the use of spiroarteriocardiorhythmography (SACRG). The patients under examination were divided into 2 groups: the group of comparison (n = 20), and the main one (n = 51). Alfa - coefficient in high (BRHF) and low (BRLF) frequencies, hemodynamic and minute volume of blood circulation (HMV, l), indexes of cardiovascular and respiratory systems synchronization and parameters of the cardiovascular system in patients with asthma were determined. Conclusions. In BA at the background of total respiratory capacity significant increase and growth of neurohumoral regulatory influences there is a significant decrease of the sympathetic link activity in the regulation of uncontrolled respiration and relative reduction of the volume velocity of inspiration, which should be taken into account when determining the severity of asthma.
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spelling doaj.art-1c5cb3408eac4719bab36ae4196214e32022-12-22T00:20:06ZengKazimierz Wielki UniversityJournal of Education, Health and Sport2391-83062018-01-0181Regulatory peculiar features of uncontrolled bronchial asthmaO. P. Romanchuk0Ya. I. Bazhora1Odessa National Medical UniversityOdessa National Medical UniversityBronchial asthma (BA) is a multifactorial disease which develops under the influence environmental factors in the presence of individual’s genetic predisposition. The mechanisms associated with the respiratory system dominate in its pathogenesis. The objective: to determine the regulatory features of the uncontrolled course of asthma. The results obtained. At the outpatient stage of treatment 71 male and female patients, mean age 41.0 ± 0.8 have been examined with the use of spiroarteriocardiorhythmography (SACRG). The patients under examination were divided into 2 groups: the group of comparison (n = 20), and the main one (n = 51). Alfa - coefficient in high (BRHF) and low (BRLF) frequencies, hemodynamic and minute volume of blood circulation (HMV, l), indexes of cardiovascular and respiratory systems synchronization and parameters of the cardiovascular system in patients with asthma were determined. Conclusions. In BA at the background of total respiratory capacity significant increase and growth of neurohumoral regulatory influences there is a significant decrease of the sympathetic link activity in the regulation of uncontrolled respiration and relative reduction of the volume velocity of inspiration, which should be taken into account when determining the severity of asthma.https://apcz.umk.pl/JEHS/article/view/25204bronchial asthmaneurohumoral regulatory influencesuncontrolled breathing
spellingShingle O. P. Romanchuk
Ya. I. Bazhora
Regulatory peculiar features of uncontrolled bronchial asthma
Journal of Education, Health and Sport
bronchial asthma
neurohumoral regulatory influences
uncontrolled breathing
title Regulatory peculiar features of uncontrolled bronchial asthma
title_full Regulatory peculiar features of uncontrolled bronchial asthma
title_fullStr Regulatory peculiar features of uncontrolled bronchial asthma
title_full_unstemmed Regulatory peculiar features of uncontrolled bronchial asthma
title_short Regulatory peculiar features of uncontrolled bronchial asthma
title_sort regulatory peculiar features of uncontrolled bronchial asthma
topic bronchial asthma
neurohumoral regulatory influences
uncontrolled breathing
url https://apcz.umk.pl/JEHS/article/view/25204
work_keys_str_mv AT opromanchuk regulatorypeculiarfeaturesofuncontrolledbronchialasthma
AT yaibazhora regulatorypeculiarfeaturesofuncontrolledbronchialasthma