The phosphorylation to acetylation/methylation cascade in transcriptional regulation: how kinases regulate transcriptional activities of DNA/histone-modifying enzymes

Abstract Transcription factors directly regulate gene expression by recognizing and binding to specific DNA sequences, involving the dynamic alterations of chromatin structure and the formation of a complex with different kinds of cofactors, like DNA/histone modifying-enzymes, chromatin remodeling f...

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Bibliographic Details
Main Authors: Pin Zhao, Samiullah Malik
Format: Article
Language:English
Published: BMC 2022-06-01
Series:Cell & Bioscience
Subjects:
Online Access:https://doi.org/10.1186/s13578-022-00821-7