Humoral immune response to campylobacter jejuni in patients with enterocolitis and Guillain-Barré syndrome

Campylobacter jejuni is one of the most important causes of diarrheal disease worldwide. In addition, it can cause neurological post-infectious sequels, such as Guillain-Barré syndrome (GBS). Humoral immune response to C. jejuni was monitored in patients with C. jejuni enterocolitis, GBS patients...

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Main Authors: Ristić Ljiljana, Kocić Branislava, Babić Tatjana, Apostolski S., Spasić Mirjana, Miljković-Selimović Biljana
Format: Article
Language:English
Published: University of Belgrade, University of Novi Sad 2012-01-01
Series:Archives of Biological Sciences
Subjects:
Online Access:http://www.doiserbia.nb.rs/img/doi/0354-4664/2012/0354-46641204349R.pdf
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author Ristić Ljiljana
Kocić Branislava
Babić Tatjana
Apostolski S.
Spasić Mirjana
Miljković-Selimović Biljana
author_facet Ristić Ljiljana
Kocić Branislava
Babić Tatjana
Apostolski S.
Spasić Mirjana
Miljković-Selimović Biljana
author_sort Ristić Ljiljana
collection DOAJ
description Campylobacter jejuni is one of the most important causes of diarrheal disease worldwide. In addition, it can cause neurological post-infectious sequels, such as Guillain-Barré syndrome (GBS). Humoral immune response to C. jejuni was monitored in patients with C. jejuni enterocolitis, GBS patients and healthy persons, by ELISA. Statistical significance between patients with enterocolitis and healthy persons, as well as among GBS patients and healthy controls, was proven. Statistical significance in IgA among the examined groups was also noticed. The highest values of IgM were found in the patients with GBS, while the highest values of IgG were found in those with enterocolitis. C. jejuni is a significant cause of antecedent infection in GBS. ELISA techniques can be considered a reliable method in determining the presence of serum antibodies in patients with enterocolitis caused by C. jejuni, as well as in patients with GBS.
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spelling doaj.art-1c6528ea52024e73a575d784304d24002022-12-21T18:30:51ZengUniversity of Belgrade, University of Novi SadArchives of Biological Sciences0354-46641821-43392012-01-016441349135510.2298/ABS1204349RHumoral immune response to campylobacter jejuni in patients with enterocolitis and Guillain-Barré syndromeRistić LjiljanaKocić BranislavaBabić TatjanaApostolski S.Spasić MirjanaMiljković-Selimović BiljanaCampylobacter jejuni is one of the most important causes of diarrheal disease worldwide. In addition, it can cause neurological post-infectious sequels, such as Guillain-Barré syndrome (GBS). Humoral immune response to C. jejuni was monitored in patients with C. jejuni enterocolitis, GBS patients and healthy persons, by ELISA. Statistical significance between patients with enterocolitis and healthy persons, as well as among GBS patients and healthy controls, was proven. Statistical significance in IgA among the examined groups was also noticed. The highest values of IgM were found in the patients with GBS, while the highest values of IgG were found in those with enterocolitis. C. jejuni is a significant cause of antecedent infection in GBS. ELISA techniques can be considered a reliable method in determining the presence of serum antibodies in patients with enterocolitis caused by C. jejuni, as well as in patients with GBS.http://www.doiserbia.nb.rs/img/doi/0354-4664/2012/0354-46641204349R.pdfC. jejunienterocolitisGBS
spellingShingle Ristić Ljiljana
Kocić Branislava
Babić Tatjana
Apostolski S.
Spasić Mirjana
Miljković-Selimović Biljana
Humoral immune response to campylobacter jejuni in patients with enterocolitis and Guillain-Barré syndrome
Archives of Biological Sciences
C. jejuni
enterocolitis
GBS
title Humoral immune response to campylobacter jejuni in patients with enterocolitis and Guillain-Barré syndrome
title_full Humoral immune response to campylobacter jejuni in patients with enterocolitis and Guillain-Barré syndrome
title_fullStr Humoral immune response to campylobacter jejuni in patients with enterocolitis and Guillain-Barré syndrome
title_full_unstemmed Humoral immune response to campylobacter jejuni in patients with enterocolitis and Guillain-Barré syndrome
title_short Humoral immune response to campylobacter jejuni in patients with enterocolitis and Guillain-Barré syndrome
title_sort humoral immune response to campylobacter jejuni in patients with enterocolitis and guillain barre syndrome
topic C. jejuni
enterocolitis
GBS
url http://www.doiserbia.nb.rs/img/doi/0354-4664/2012/0354-46641204349R.pdf
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