Developmental pathways linked to the vulnerability of adult midbrain dopaminergic neurons to neurodegeneration
The degeneration of dopaminergic and other neurons in the aging brain is considered a process starting well beyond the infantile and juvenile period. In contrast to other dopamine-associated neuropsychiatric disorders, such as schizophrenia and drug addiction, typically diagnosed during adolescence...
Main Author: | Nilima Prakash |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2022-12-01
|
Series: | Frontiers in Molecular Neuroscience |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fnmol.2022.1071731/full |
Similar Items
-
A WNT1-regulated developmental gene cascade prevents dopaminergic neurodegeneration in adult En1+/− mice
by: Jingzhong Zhang, et al.
Published: (2015-10-01) -
Molecular Programming of Mesodiencephalic Dopaminergic Neuronal Subsets
by: Marten P. Smidt
Published: (2017-07-01) -
From 2D to 3D: Development of Monolayer Dopaminergic Neuronal and Midbrain Organoid Cultures for Parkinson’s Disease Modeling and Regenerative Therapy
by: Yee Jie Yeap, et al.
Published: (2023-01-01) -
The Convergence of Alpha-Synuclein, Mitochondrial, and Lysosomal Pathways in Vulnerability of Midbrain Dopaminergic Neurons in Parkinson’s Disease
by: Georgia Minakaki, et al.
Published: (2020-12-01) -
Crosstalk of Intercellular Signaling Pathways in the Generation of Midbrain Dopaminergic Neurons In Vivo and from Stem Cells
by: Claude Brodski, et al.
Published: (2019-01-01)