Hidden among the crowd: differential DNA methylation-expression correlations in cancer occur at important oncogenic pathways

DNA methylation is a frequent epigenetic mechanism that participates in transcriptional repression. Variations in DNA methylation with respect to gene expression are constant, and, for unknown reasons, some genes with highly methylated promoters are sometimes overexpressed. In this study we have ana...

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Bibliographic Details
Main Author: Adrián Mosquera Orgueira
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-05-01
Series:Frontiers in Genetics
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2015.00163/full