Nonlinear Dynamics of a Piecewise Modified ABC Fractional-Order Leukemia Model with Symmetric Numerical Simulations

In this study, we introduce a nonlinear leukemia dynamical system for a piecewise modified ABC fractional-order derivative and analyze it for the theoretical as well computational works and examine the crossover effect of the model. For the crossover behavior of the operators, we presume a division...

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Main Authors: Hasib Khan, Jehad Alzabut, Wafa F. Alfwzan, Haseena Gulzar
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Symmetry
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Online Access:https://www.mdpi.com/2073-8994/15/7/1338
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author Hasib Khan
Jehad Alzabut
Wafa F. Alfwzan
Haseena Gulzar
author_facet Hasib Khan
Jehad Alzabut
Wafa F. Alfwzan
Haseena Gulzar
author_sort Hasib Khan
collection DOAJ
description In this study, we introduce a nonlinear leukemia dynamical system for a piecewise modified ABC fractional-order derivative and analyze it for the theoretical as well computational works and examine the crossover effect of the model. For the crossover behavior of the operators, we presume a division of the period of study <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mo>[</mo><mn>0</mn><mo>,</mo><msub><mi>t</mi><mn>2</mn></msub><mo>]</mo></mrow></semantics></math></inline-formula> in two subclasses as <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><msub><mi mathvariant="script">I</mi><mn>1</mn></msub><mo>=</mo><mrow><mo>[</mo><mn>0</mn><mo>,</mo><msub><mi>t</mi><mn>1</mn></msub><mo>]</mo></mrow></mrow></semantics></math></inline-formula>, <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><msub><mi mathvariant="script">I</mi><mn>2</mn></msub><mo>=</mo><mrow><mo>[</mo><msub><mi>t</mi><mn>1</mn></msub><mo>,</mo><msub><mi>t</mi><mn>2</mn></msub><mo>]</mo></mrow></mrow></semantics></math></inline-formula>, for <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><msub><mi>t</mi><mn>1</mn></msub><mo>,</mo><msub><mi>t</mi><mn>2</mn></msub><mo>∈</mo><mi mathvariant="double-struck">R</mi></mrow></semantics></math></inline-formula> with <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><msub><mi>t</mi><mn>1</mn></msub><mo><</mo><msub><mi>t</mi><mn>2</mn></msub></mrow></semantics></math></inline-formula>. In <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><msub><mi mathvariant="script">I</mi><mn>1</mn></msub></semantics></math></inline-formula>, the classical derivative is considered for the study of the leukemia growth while in <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><msub><mi mathvariant="script">I</mi><mn>2</mn></msub></semantics></math></inline-formula> we presume modified ABC fractional differential operator. As a result, the study is initiated in the piecewise modified ABC sense of derivative for the dynamical systems. The novel constructed model is then studied for the solution existence and stability as well computational results. The symmetry in dynamics for all the three classes can be graphically observed in the presented six plots.
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spelling doaj.art-1c6ab54ca6f64250bd0223a186a49b582023-11-18T21:33:41ZengMDPI AGSymmetry2073-89942023-06-01157133810.3390/sym15071338Nonlinear Dynamics of a Piecewise Modified ABC Fractional-Order Leukemia Model with Symmetric Numerical SimulationsHasib Khan0Jehad Alzabut1Wafa F. Alfwzan2Haseena Gulzar3Department of Mathematics and Sciences, Prince Sultan University, Riyadh 11586, Saudi ArabiaDepartment of Mathematics and Sciences, Prince Sultan University, Riyadh 11586, Saudi ArabiaDepartment of Mathematical Sciences, College of Science, Princess Nourah bint Abdulrahman University, P.O. Box 84428, Riyadh 11671, Saudi ArabiaDepartment of Biotechnology, Shaheed Benazir Bhutto Uniersity, Sheringal, Dir Upper 18000, PakistanIn this study, we introduce a nonlinear leukemia dynamical system for a piecewise modified ABC fractional-order derivative and analyze it for the theoretical as well computational works and examine the crossover effect of the model. For the crossover behavior of the operators, we presume a division of the period of study <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mo>[</mo><mn>0</mn><mo>,</mo><msub><mi>t</mi><mn>2</mn></msub><mo>]</mo></mrow></semantics></math></inline-formula> in two subclasses as <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><msub><mi mathvariant="script">I</mi><mn>1</mn></msub><mo>=</mo><mrow><mo>[</mo><mn>0</mn><mo>,</mo><msub><mi>t</mi><mn>1</mn></msub><mo>]</mo></mrow></mrow></semantics></math></inline-formula>, <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><msub><mi mathvariant="script">I</mi><mn>2</mn></msub><mo>=</mo><mrow><mo>[</mo><msub><mi>t</mi><mn>1</mn></msub><mo>,</mo><msub><mi>t</mi><mn>2</mn></msub><mo>]</mo></mrow></mrow></semantics></math></inline-formula>, for <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><msub><mi>t</mi><mn>1</mn></msub><mo>,</mo><msub><mi>t</mi><mn>2</mn></msub><mo>∈</mo><mi mathvariant="double-struck">R</mi></mrow></semantics></math></inline-formula> with <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><msub><mi>t</mi><mn>1</mn></msub><mo><</mo><msub><mi>t</mi><mn>2</mn></msub></mrow></semantics></math></inline-formula>. In <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><msub><mi mathvariant="script">I</mi><mn>1</mn></msub></semantics></math></inline-formula>, the classical derivative is considered for the study of the leukemia growth while in <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><msub><mi mathvariant="script">I</mi><mn>2</mn></msub></semantics></math></inline-formula> we presume modified ABC fractional differential operator. As a result, the study is initiated in the piecewise modified ABC sense of derivative for the dynamical systems. The novel constructed model is then studied for the solution existence and stability as well computational results. The symmetry in dynamics for all the three classes can be graphically observed in the presented six plots.https://www.mdpi.com/2073-8994/15/7/1338piecewise modified ABC derivativeleukemia mathematical modelexistence of solutionsHyers–Ulam stabilitycrossover behavior
spellingShingle Hasib Khan
Jehad Alzabut
Wafa F. Alfwzan
Haseena Gulzar
Nonlinear Dynamics of a Piecewise Modified ABC Fractional-Order Leukemia Model with Symmetric Numerical Simulations
Symmetry
piecewise modified ABC derivative
leukemia mathematical model
existence of solutions
Hyers–Ulam stability
crossover behavior
title Nonlinear Dynamics of a Piecewise Modified ABC Fractional-Order Leukemia Model with Symmetric Numerical Simulations
title_full Nonlinear Dynamics of a Piecewise Modified ABC Fractional-Order Leukemia Model with Symmetric Numerical Simulations
title_fullStr Nonlinear Dynamics of a Piecewise Modified ABC Fractional-Order Leukemia Model with Symmetric Numerical Simulations
title_full_unstemmed Nonlinear Dynamics of a Piecewise Modified ABC Fractional-Order Leukemia Model with Symmetric Numerical Simulations
title_short Nonlinear Dynamics of a Piecewise Modified ABC Fractional-Order Leukemia Model with Symmetric Numerical Simulations
title_sort nonlinear dynamics of a piecewise modified abc fractional order leukemia model with symmetric numerical simulations
topic piecewise modified ABC derivative
leukemia mathematical model
existence of solutions
Hyers–Ulam stability
crossover behavior
url https://www.mdpi.com/2073-8994/15/7/1338
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AT wafafalfwzan nonlineardynamicsofapiecewisemodifiedabcfractionalorderleukemiamodelwithsymmetricnumericalsimulations
AT haseenagulzar nonlineardynamicsofapiecewisemodifiedabcfractionalorderleukemiamodelwithsymmetricnumericalsimulations