Targeting brain tumor cAMP: the case for sex-specific therapeutics

Targeting brain tumor cAMP: the case for sex-specific therapeutics

A relationship between cyclic adenosine 3’, 5’-monophosphate (cAMP) levels and brain tumor biology has been evident for nearly as long as cAMP and its synthetase, adenylate cyclase (ADCY) have been known. The importance of the pathway in brain tumorigenesis has been demonstrated in vitro and in mu...

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Bibliographic Details
Main Authors: Nicole M Warrington, Tao eSun, Joshua B Rubin
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-07-01
Series:Frontiers in Pharmacology
Subjects:
brain tumors
cAMP
PDE
sex differences
primary cilia
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2015.00153/full

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