Development and optimization of fast dissolving oro-dispersible films of granisetron HCl using Box–Behnken statistical design

Development and optimization of fast dissolving oro-dispersible films of granisetron HCl using Box–Behnken statistical design

The aim was to develop and optimize fast dissolving oro-dispersible films of granisetron hydrochloride (GH) by two-factor, three-level Box–Behnken design as the two independent variables such as X1 (polymer) and X2 (plasticizer) were selected on the basis of the preliminary studies carried out befor...

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Bibliographic Details
Main Authors: Hema Chaudhary, Samita Gauri, Permender Rathee, Vikash Kumar
Format: Article
Language:English
Published: Faculty of Pharmacy, Cairo University 2013-12-01
Series:Bulletin of Faculty of Pharmacy Cairo University
Subjects:
Fast oro-dispersible film
Drug design
Box–Behnken design
Optimization
Online Access:http://www.sciencedirect.com/science/article/pii/S1110093113000264

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