Comparison of different approaches for direct coupling of solid-phase microextraction to mass spectrometry for drugs of abuse analysis in plasma

Comparison of different approaches for direct coupling of solid-phase microextraction to mass spectrometry for drugs of abuse analysis in plasma

The direct coupling of solid-phase microextraction (SPME) to mass spectrometry (MS) (SPME-MS) has proven to be an effective method for the fast screening and quantitative analysis of compounds in complex matrices such as blood and plasma. In recent years, our lab has developed three novel SPME-MS te...

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Bibliographic Details
Main Authors: Wei Zhou, Martyna N. Wieczorek, Runshan Will Jiang, Janusz Pawliszyn
Format: Article
Language:English
Published: Elsevier 2023-02-01
Series:Journal of Pharmaceutical Analysis
Subjects:
Solid-phase microextraction
Mass spectrometry
Microfluidic open interface
Coated blade spray
Probe electrospray ionization
Drug of abuse
Online Access:http://www.sciencedirect.com/science/article/pii/S2095177922001009

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http://www.sciencedirect.com/science/article/pii/S2095177922001009

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