Microorganisms in the reproductive system and probiotic's regulatory effects on reproductive health
The presence of microbial communities in the reproductive tract has been revealed, and this resident microbiota is involved in the maintenance of health. Intentional modulation via probiotics has been proposed as a possible strategy to enhance reproductive health and reduce the risk of diseases. The...
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| Format: | Article |
| Language: | English |
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Elsevier
2022-01-01
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| Series: | Computational and Structural Biotechnology Journal |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2001037022000927 |
| _version_ | 1797978201255837696 |
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| author | Tao Feng Yan Liu |
| author_facet | Tao Feng Yan Liu |
| author_sort | Tao Feng |
| collection | DOAJ |
| description | The presence of microbial communities in the reproductive tract has been revealed, and this resident microbiota is involved in the maintenance of health. Intentional modulation via probiotics has been proposed as a possible strategy to enhance reproductive health and reduce the risk of diseases. The male seminal microbiota has been suggested as an important factor that influences a couple’s health, pregnancy outcomes, and offspring health. Probiotics have been reported to play a role in male fertility and to affect the health of mothers and offspring. While the female reproductive microbiota is more complicated and has been identified in both the upper and lower reproductive systems, they together contribute to health maintenance. Probiotics have shown regulatory effects on the female reproductive tract, thereby contributing to homeostasis of the tract and influencing the health of offspring. Further, through transmission of bacteria or through other indirect mechanisms, the parent’s reproductive microbiota and probiotic intervention influence infant gut colonization and immunity development, with potential health consequences. In vitro and in vivo studies have explored the mechanisms underlying the benefits of probiotic administration and intervention, and an array of positive results, such as modulation of microbiota composition, regulation of metabolism, promotion of the epithelial barrier, and improvement of immune function, have been observed. Herein, we review the state of the art in reproductive system microbiota and its role in health and reproduction, as well as the beneficial effects of probiotics on reproductive health and their contributions to the prevention of associated diseases. |
| first_indexed | 2024-04-11T05:20:13Z |
| format | Article |
| id | doaj.art-1c6f9e13eebf4779921eba1f5c747bd1 |
| institution | Directory Open Access Journal |
| issn | 2001-0370 |
| language | English |
| last_indexed | 2024-04-11T05:20:13Z |
| publishDate | 2022-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Computational and Structural Biotechnology Journal |
| spelling | doaj.art-1c6f9e13eebf4779921eba1f5c747bd12022-12-24T04:51:47ZengElsevierComputational and Structural Biotechnology Journal2001-03702022-01-012015411553Microorganisms in the reproductive system and probiotic's regulatory effects on reproductive healthTao Feng0Yan Liu1Institute of Animal Husbandry and Veterinary Medicine (IAHVM), Beijing Academy of Agriculture and Forestry Sciences (BAAFS), Beijing, China; Sino-US Joint Laboratory of Animal Science, Beijing Academy of Agriculture and Forestry Sciences, Beijing, ChinaInstitute of Animal Husbandry and Veterinary Medicine (IAHVM), Beijing Academy of Agriculture and Forestry Sciences (BAAFS), Beijing, China; Sino-US Joint Laboratory of Animal Science, Beijing Academy of Agriculture and Forestry Sciences, Beijing, China; Corresponding author at: Institute of Animal Husbandry and Veterinary Medicine (IAHVM), Beijing Academy of Agriculture and Forestry Sciences (BAAFS), Beijing, China.The presence of microbial communities in the reproductive tract has been revealed, and this resident microbiota is involved in the maintenance of health. Intentional modulation via probiotics has been proposed as a possible strategy to enhance reproductive health and reduce the risk of diseases. The male seminal microbiota has been suggested as an important factor that influences a couple’s health, pregnancy outcomes, and offspring health. Probiotics have been reported to play a role in male fertility and to affect the health of mothers and offspring. While the female reproductive microbiota is more complicated and has been identified in both the upper and lower reproductive systems, they together contribute to health maintenance. Probiotics have shown regulatory effects on the female reproductive tract, thereby contributing to homeostasis of the tract and influencing the health of offspring. Further, through transmission of bacteria or through other indirect mechanisms, the parent’s reproductive microbiota and probiotic intervention influence infant gut colonization and immunity development, with potential health consequences. In vitro and in vivo studies have explored the mechanisms underlying the benefits of probiotic administration and intervention, and an array of positive results, such as modulation of microbiota composition, regulation of metabolism, promotion of the epithelial barrier, and improvement of immune function, have been observed. Herein, we review the state of the art in reproductive system microbiota and its role in health and reproduction, as well as the beneficial effects of probiotics on reproductive health and their contributions to the prevention of associated diseases.http://www.sciencedirect.com/science/article/pii/S2001037022000927ReproductionReproductive systemReproductive microbiomeProbioticRegulation effect |
| spellingShingle | Tao Feng Yan Liu Microorganisms in the reproductive system and probiotic's regulatory effects on reproductive health Computational and Structural Biotechnology Journal Reproduction Reproductive system Reproductive microbiome Probiotic Regulation effect |
| title | Microorganisms in the reproductive system and probiotic's regulatory effects on reproductive health |
| title_full | Microorganisms in the reproductive system and probiotic's regulatory effects on reproductive health |
| title_fullStr | Microorganisms in the reproductive system and probiotic's regulatory effects on reproductive health |
| title_full_unstemmed | Microorganisms in the reproductive system and probiotic's regulatory effects on reproductive health |
| title_short | Microorganisms in the reproductive system and probiotic's regulatory effects on reproductive health |
| title_sort | microorganisms in the reproductive system and probiotic s regulatory effects on reproductive health |
| topic | Reproduction Reproductive system Reproductive microbiome Probiotic Regulation effect |
| url | http://www.sciencedirect.com/science/article/pii/S2001037022000927 |
| work_keys_str_mv | AT taofeng microorganismsinthereproductivesystemandprobioticsregulatoryeffectsonreproductivehealth AT yanliu microorganismsinthereproductivesystemandprobioticsregulatoryeffectsonreproductivehealth |