Rasmussen's encephalitis. Clinical case of surgical treatment

The article presents literary data on the clinical course, diagnostics and treatment of Rasmussen's encephalitis in children. Epileptic attacks at Rasmussen's encephalitis are resistant to the anti-convulsion therapy and. progressing cerebral atrophy collateral to the motor disorders are r...

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Bibliographic Details
Main Authors: S. N. Larionov, V. A. Sorokovikov, Yu. A. Alexandrov, E. B. Khaykina, E. K. Pulyaevskaya
Format: Article
Language:Russian
Published: Scientific Сentre for Family Health and Human Reproduction Problems 2013-02-01
Series:Acta Biomedica Scientifica
Subjects:
Online Access:https://www.actabiomedica.ru/jour/article/view/1402
Description
Summary:The article presents literary data on the clinical course, diagnostics and treatment of Rasmussen's encephalitis in children. Epileptic attacks at Rasmussen's encephalitis are resistant to the anti-convulsion therapy and. progressing cerebral atrophy collateral to the motor disorders are revealed at magnetic resonance imaging. Used methods of conservative treatment are various and. include anti-epilepsy and antiviral medicines, ketogenic diet, plasmapheresis, immunosuppression and. transcranial magnetic stimulation. Surgical treatment is presented. by functional hemispherectomy. The article presents clinical case of 14 years old. girl with Rasmussen's encephalitis. In the beginning of the disease antiviral medicines and. steroid therapy (acyclovir, dexamethasone) were used. Later various methods of physical rehabilitation and. operative methods for removal of spasticity were used. At preoperative stage polytherapy including carbamazepine, lamotrigine and topiramate were used. Course of postoperative period was complicated by the development of refractory focal epileptic status and. series of attacks. After functional hemispherectomy polytherapy with use of leviracetam, topiramate and. valproate was selected. At the backgrould of complex therapy the positive effect in the form of decrease of frequency of attacks more than 75 % was noted.
ISSN:2541-9420
2587-9596