Rasmussen's encephalitis. Clinical case of surgical treatment
The article presents literary data on the clinical course, diagnostics and treatment of Rasmussen's encephalitis in children. Epileptic attacks at Rasmussen's encephalitis are resistant to the anti-convulsion therapy and. progressing cerebral atrophy collateral to the motor disorders are r...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | Russian |
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Scientific Сentre for Family Health and Human Reproduction Problems
2013-02-01
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| Series: | Acta Biomedica Scientifica |
| Subjects: | |
| Online Access: | https://www.actabiomedica.ru/jour/article/view/1402 |
| _version_ | 1797237530909736960 |
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| author | S. N. Larionov V. A. Sorokovikov Yu. A. Alexandrov E. B. Khaykina E. K. Pulyaevskaya |
| author_facet | S. N. Larionov V. A. Sorokovikov Yu. A. Alexandrov E. B. Khaykina E. K. Pulyaevskaya |
| author_sort | S. N. Larionov |
| collection | DOAJ |
| description | The article presents literary data on the clinical course, diagnostics and treatment of Rasmussen's encephalitis in children. Epileptic attacks at Rasmussen's encephalitis are resistant to the anti-convulsion therapy and. progressing cerebral atrophy collateral to the motor disorders are revealed at magnetic resonance imaging. Used methods of conservative treatment are various and. include anti-epilepsy and antiviral medicines, ketogenic diet, plasmapheresis, immunosuppression and. transcranial magnetic stimulation. Surgical treatment is presented. by functional hemispherectomy. The article presents clinical case of 14 years old. girl with Rasmussen's encephalitis. In the beginning of the disease antiviral medicines and. steroid therapy (acyclovir, dexamethasone) were used. Later various methods of physical rehabilitation and. operative methods for removal of spasticity were used. At preoperative stage polytherapy including carbamazepine, lamotrigine and topiramate were used. Course of postoperative period was complicated by the development of refractory focal epileptic status and. series of attacks. After functional hemispherectomy polytherapy with use of leviracetam, topiramate and. valproate was selected. At the backgrould of complex therapy the positive effect in the form of decrease of frequency of attacks more than 75 % was noted. |
| first_indexed | 2024-03-08T12:20:37Z |
| format | Article |
| id | doaj.art-1c75f5a6a58d40e8bb265544c2260335 |
| institution | Directory Open Access Journal |
| issn | 2541-9420 2587-9596 |
| language | Russian |
| last_indexed | 2024-04-24T17:21:13Z |
| publishDate | 2013-02-01 |
| publisher | Scientific Сentre for Family Health and Human Reproduction Problems |
| record_format | Article |
| series | Acta Biomedica Scientifica |
| spelling | doaj.art-1c75f5a6a58d40e8bb265544c22603352024-03-28T07:49:09ZrusScientific Сentre for Family Health and Human Reproduction ProblemsActa Biomedica Scientifica2541-94202587-95962013-02-010144481348Rasmussen's encephalitis. Clinical case of surgical treatmentS. N. Larionov0V. A. Sorokovikov1Yu. A. Alexandrov2E. B. Khaykina3E. K. Pulyaevskaya4ГБУЗ «Иркутская государственная областная детская клиническая больница»; ФГБУ «Научный центр реконструктивной и восстановительной хирургии» СО РАМН; ГБОУ ДПО «Иркутская государственная медицинская академия последипломного образования» Минздрава РФФГБУ «Научный центр реконструктивной и восстановительной хирургии» СО РАМН; ГБОУ ДПО «Иркутская государственная медицинская академия последипломного образования» Минздрава РФМАУЗ «Городская Ивано-Матренинская городская детская клиническая больница»ГБУЗ «Иркутская государственная областная детская клиническая больница»ГБУЗ «Иркутская государственная областная детская клиническая больница»The article presents literary data on the clinical course, diagnostics and treatment of Rasmussen's encephalitis in children. Epileptic attacks at Rasmussen's encephalitis are resistant to the anti-convulsion therapy and. progressing cerebral atrophy collateral to the motor disorders are revealed at magnetic resonance imaging. Used methods of conservative treatment are various and. include anti-epilepsy and antiviral medicines, ketogenic diet, plasmapheresis, immunosuppression and. transcranial magnetic stimulation. Surgical treatment is presented. by functional hemispherectomy. The article presents clinical case of 14 years old. girl with Rasmussen's encephalitis. In the beginning of the disease antiviral medicines and. steroid therapy (acyclovir, dexamethasone) were used. Later various methods of physical rehabilitation and. operative methods for removal of spasticity were used. At preoperative stage polytherapy including carbamazepine, lamotrigine and topiramate were used. Course of postoperative period was complicated by the development of refractory focal epileptic status and. series of attacks. After functional hemispherectomy polytherapy with use of leviracetam, topiramate and. valproate was selected. At the backgrould of complex therapy the positive effect in the form of decrease of frequency of attacks more than 75 % was noted.https://www.actabiomedica.ru/jour/article/view/1402rasmussen's encephalitisfunctional hemispherectomylevetiracetamvalproatetopiramate |
| spellingShingle | S. N. Larionov V. A. Sorokovikov Yu. A. Alexandrov E. B. Khaykina E. K. Pulyaevskaya Rasmussen's encephalitis. Clinical case of surgical treatment Acta Biomedica Scientifica rasmussen's encephalitis functional hemispherectomy levetiracetam valproate topiramate |
| title | Rasmussen's encephalitis. Clinical case of surgical treatment |
| title_full | Rasmussen's encephalitis. Clinical case of surgical treatment |
| title_fullStr | Rasmussen's encephalitis. Clinical case of surgical treatment |
| title_full_unstemmed | Rasmussen's encephalitis. Clinical case of surgical treatment |
| title_short | Rasmussen's encephalitis. Clinical case of surgical treatment |
| title_sort | rasmussen s encephalitis clinical case of surgical treatment |
| topic | rasmussen's encephalitis functional hemispherectomy levetiracetam valproate topiramate |
| url | https://www.actabiomedica.ru/jour/article/view/1402 |
| work_keys_str_mv | AT snlarionov rasmussensencephalitisclinicalcaseofsurgicaltreatment AT vasorokovikov rasmussensencephalitisclinicalcaseofsurgicaltreatment AT yuaalexandrov rasmussensencephalitisclinicalcaseofsurgicaltreatment AT ebkhaykina rasmussensencephalitisclinicalcaseofsurgicaltreatment AT ekpulyaevskaya rasmussensencephalitisclinicalcaseofsurgicaltreatment |