CDC25C Protein Expression Correlates with Tumor Differentiation and Clinical Outcomes in Lung Adenocarcinoma
Given that, even after multimodal therapy, early-stage lung cancer (LC) often recurs, novel prognostic markers to help guide therapy are highly desired. The mRNA levels of cell division cycle 25C (CDC25C), a phosphatase that regulates G2/M cell cycle transition in malignant cells, correlate with poo...
Main Authors: | Esther Stern, Guy Pines, Li Or Lazar, Gilad W. Vainer, Nitzan Beltran, Omri Dodi, Lika Gamaev, Ofir Hikri Simon, Michal Abraham, Hanna Wald, Amnon Peled, Ori Wald |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-01-01
|
Series: | Biomedicines |
Subjects: | |
Online Access: | https://www.mdpi.com/2227-9059/11/2/362 |
Similar Items
-
CDC25C as a Predictive Biomarker for Immune Checkpoint Inhibitors in Patients With Lung Adenocarcinoma
by: Wengang Zhang, et al.
Published: (2022-04-01) -
Polymorphism and CDC25A Gene Expression in Pancreatic Cancer
by: Başar Aksoy, et al.
Published: (2016-03-01) -
Identification of CDC25-P1306L, a novel mutant allele of CDC25, conferring tolerance to multiple stresses associated with food production on Saccharomyces cerevisiae
by: Youji Nakagawa, et al.
Published: (2019-01-01) -
CDC45 promotes the stemness and metastasis in lung adenocarcinoma by affecting the cell cycle
by: Yafeng Liu, et al.
Published: (2024-04-01) -
Shikonin inhibits cancer cell cycling by targeting Cdc25s
by: Shoude Zhang, et al.
Published: (2019-01-01)