Protective effects of DPP-4 inhibitor on podocyte injury in glomerular diseases

Protective effects of DPP-4 inhibitor on podocyte injury in glomerular diseases

Abstract Background Dipeptidyl peptidase-4 (DPP-4) is a serine protease that inhibits the degradation of glucagon-like peptide 1. DPP-4 inhibitors are used worldwide to treat type 2 diabetes mellitus and were recently shown to have pleiotropic effects such as anti-oxidant, anti-inflammatory, and ant...

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Bibliographic Details
Main Authors: Ayano Kubo, Teruo Hidaka, Maiko Nakayama, Yu Sasaki, Miyuki Takagi, Hitoshi Suzuki, Yusuke Suzuki
Format: Article
Language:English
Published: BMC 2020-09-01
Series:BMC Nephrology
Subjects:
DPP-4
Podocyte
Glomerular disease
Synaptopodin
Saxagliptin
Online Access:http://link.springer.com/article/10.1186/s12882-020-02060-9

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