Platelet-Derived Factor V Is an Important Determinant of the Metastatic Potential of Circulating Tumor Cells

Platelet-Derived Factor V Is an Important Determinant of the Metastatic Potential of Circulating Tumor Cells

Factor V (FV) is a critical component in the blood coagulation cascade. In patients, FV inhibitors have been reported to be associated with malignancy. FV is present in plasma and platelets, which exhibit physical and functional differences. However, the functions of FV in cancer progression remain...

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Bibliographic Details
Main Authors: Xin Deng, Ziqian Feng, Luochen Zhu, Ni Chen, Yifei Deng, Yongjie Li, Rong Li, Liqun Wang, Mao Luo, Jianbo Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Oncology
Subjects:
platelets
factor V
tissue factor pathway inhibitor
metastasis
coagulation cascade
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.558306/full

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