Association between gestational diabetes and 6-year incident diabetes: results from the Hispanic Community Health Study/Study of Latinos (HCHS/SOL)
Objective Type 2 diabetes and gestational diabetes (GDM) disproportionately affect those of Hispanic/Latino heritage. This study examined the association between GDM and prevalent and incident diabetes in a community-based study of Hispanic/Latina women living in the USA.Methods Participants were wo...
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| Format: | Article |
| Language: | English |
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BMJ Publishing Group
2022-12-01
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| Series: | BMJ Open Diabetes Research & Care |
| Online Access: | https://drc.bmj.com/content/10/6/e002980.full |
| _version_ | 1827905719475634176 |
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| author | Sarah S Casagrande Daniela Sotres-Alvarez Linda Gallo Jeffrey S Gonzalez Marisa Judith Perera M Larissa Avilés-Santa Melissa Simon Michelle Kominiarek Gregory Talavera Alison M Stuebe JoNell Potter Carmen Isasi Keith Rust Catherine Cowie |
| author_facet | Sarah S Casagrande Daniela Sotres-Alvarez Linda Gallo Jeffrey S Gonzalez Marisa Judith Perera M Larissa Avilés-Santa Melissa Simon Michelle Kominiarek Gregory Talavera Alison M Stuebe JoNell Potter Carmen Isasi Keith Rust Catherine Cowie |
| author_sort | Sarah S Casagrande |
| collection | DOAJ |
| description | Objective Type 2 diabetes and gestational diabetes (GDM) disproportionately affect those of Hispanic/Latino heritage. This study examined the association between GDM and prevalent and incident diabetes in a community-based study of Hispanic/Latina women living in the USA.Methods Participants were women aged 18–74 years in the Hispanic Community Health Study/Study of Latinos who had at least one pregnancy and had information on self-reported history of GDM at baseline (n=6389). Logistic regression was used to determine the association between GDM and prevalent (2008–2011) and incident (2014–2017) diabetes and interactions between GDM and risk factors for incident diabetes.Results At baseline, 8.7% of participants reported a history of GDM and 18.6% had prevalent diabetes. Women with Mexican heritage had the highest prevalence of GDM history (11.3%) vs women of Cuban (5.0%), Central American (4.9%), and South American (3.8%) heritage (p<0.001 for each comparison to Mexican heritage). Women with self-reported GDM were four times more likely to have prevalent diabetes compared with women without GDM, after adjusting for sociodemographic characteristics and cardiometabolic risk factors (adjusted OR (aOR)=3.94, 95% CI 2.75 to 5.64). Overall incidence of diabetes was 14.3/100 women. Women with GDM at baseline increased their odds of incident diabetes by threefold compared with women without GDM (aOR=3.25, 95% CI 2.09 to 5.05). Women with Cuban or Puerto Rican heritage and GDM had significantly higher odds of incident diabetes compared with women with Mexican heritage (aOR=2.15, 95% CI 1.17 to 3.95; aOR=1.95, 95% CI 1.07 to 3.55, respectively).Conclusion Self-reported GDM was significantly associated with a threefold higher risk of incident diabetes among Hispanic/Latino women in the USA even after adjusting for several significant predictors of diabetes. |
| first_indexed | 2024-03-13T00:45:13Z |
| format | Article |
| id | doaj.art-1c7e7f3bdb86427ea57df853b1cec21b |
| institution | Directory Open Access Journal |
| issn | 2052-4897 |
| language | English |
| last_indexed | 2024-03-13T00:45:13Z |
| publishDate | 2022-12-01 |
| publisher | BMJ Publishing Group |
| record_format | Article |
| series | BMJ Open Diabetes Research & Care |
| spelling | doaj.art-1c7e7f3bdb86427ea57df853b1cec21b2023-07-09T06:00:06ZengBMJ Publishing GroupBMJ Open Diabetes Research & Care2052-48972022-12-0110610.1136/bmjdrc-2022-002980Association between gestational diabetes and 6-year incident diabetes: results from the Hispanic Community Health Study/Study of Latinos (HCHS/SOL)Sarah S Casagrande0Daniela Sotres-Alvarez1Linda Gallo2Jeffrey S Gonzalez3Marisa Judith Perera4M Larissa Avilés-Santa5Melissa Simon6Michelle Kominiarek7Gregory Talavera8Alison M Stuebe9JoNell Potter10Carmen Isasi11Keith Rust12Catherine Cowie13Public Health Research, DLH Holdings Corporation, Atlanta, Georgia, USADepartment of Biostatistics, UNC Health Care System, Chapel Hill, North Carolina, USADepartment of Psychology, San Diego State University, San Diego, California, USADepartments of Medicine and Epidemiology & Population Health, Albert Einstein College of Medicine, Bronx, New York, USADepartment of Psychiatry and Behavioral Sciences, University of Miami Health System, Miami, Florida, USANational Institute of Minority Health and Health Disparities, Division of Intramural Research, Bethesda, Maryland, USAFeinberg School of Medicine, Northwestern University, Chicago, Illinois, USAFeinberg School of Medicine, Northwestern University, Chicago, Illinois, USADepartment of Psychology, San Diego State University, San Diego, California, USADepartment of Obsterics & Gynecology, University of North Carolina, Chapel Hill, North Carolina, USADepartment of Obstetrics & Gynecology, University of Miami Health System, Miami, Florida, USADepartment of Epidemiology & Population Health, Albert Einstein College of Medicine, Bronx, New York, USAWestat Inc, Rockville, Maryland, USADivision of Diabetes, Endocrinology, & Metabolic Diseases, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland, USAObjective Type 2 diabetes and gestational diabetes (GDM) disproportionately affect those of Hispanic/Latino heritage. This study examined the association between GDM and prevalent and incident diabetes in a community-based study of Hispanic/Latina women living in the USA.Methods Participants were women aged 18–74 years in the Hispanic Community Health Study/Study of Latinos who had at least one pregnancy and had information on self-reported history of GDM at baseline (n=6389). Logistic regression was used to determine the association between GDM and prevalent (2008–2011) and incident (2014–2017) diabetes and interactions between GDM and risk factors for incident diabetes.Results At baseline, 8.7% of participants reported a history of GDM and 18.6% had prevalent diabetes. Women with Mexican heritage had the highest prevalence of GDM history (11.3%) vs women of Cuban (5.0%), Central American (4.9%), and South American (3.8%) heritage (p<0.001 for each comparison to Mexican heritage). Women with self-reported GDM were four times more likely to have prevalent diabetes compared with women without GDM, after adjusting for sociodemographic characteristics and cardiometabolic risk factors (adjusted OR (aOR)=3.94, 95% CI 2.75 to 5.64). Overall incidence of diabetes was 14.3/100 women. Women with GDM at baseline increased their odds of incident diabetes by threefold compared with women without GDM (aOR=3.25, 95% CI 2.09 to 5.05). Women with Cuban or Puerto Rican heritage and GDM had significantly higher odds of incident diabetes compared with women with Mexican heritage (aOR=2.15, 95% CI 1.17 to 3.95; aOR=1.95, 95% CI 1.07 to 3.55, respectively).Conclusion Self-reported GDM was significantly associated with a threefold higher risk of incident diabetes among Hispanic/Latino women in the USA even after adjusting for several significant predictors of diabetes.https://drc.bmj.com/content/10/6/e002980.full |
| spellingShingle | Sarah S Casagrande Daniela Sotres-Alvarez Linda Gallo Jeffrey S Gonzalez Marisa Judith Perera M Larissa Avilés-Santa Melissa Simon Michelle Kominiarek Gregory Talavera Alison M Stuebe JoNell Potter Carmen Isasi Keith Rust Catherine Cowie Association between gestational diabetes and 6-year incident diabetes: results from the Hispanic Community Health Study/Study of Latinos (HCHS/SOL) BMJ Open Diabetes Research & Care |
| title | Association between gestational diabetes and 6-year incident diabetes: results from the Hispanic Community Health Study/Study of Latinos (HCHS/SOL) |
| title_full | Association between gestational diabetes and 6-year incident diabetes: results from the Hispanic Community Health Study/Study of Latinos (HCHS/SOL) |
| title_fullStr | Association between gestational diabetes and 6-year incident diabetes: results from the Hispanic Community Health Study/Study of Latinos (HCHS/SOL) |
| title_full_unstemmed | Association between gestational diabetes and 6-year incident diabetes: results from the Hispanic Community Health Study/Study of Latinos (HCHS/SOL) |
| title_short | Association between gestational diabetes and 6-year incident diabetes: results from the Hispanic Community Health Study/Study of Latinos (HCHS/SOL) |
| title_sort | association between gestational diabetes and 6 year incident diabetes results from the hispanic community health study study of latinos hchs sol |
| url | https://drc.bmj.com/content/10/6/e002980.full |
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