Consecutive daily administration of intratracheal surfactant and human umbilical cord-derived mesenchymal stem cells attenuates hyperoxia-induced lung injury in neonatal rats

Consecutive daily administration of intratracheal surfactant and human umbilical cord-derived mesenchymal stem cells attenuates hyperoxia-induced lung injury in neonatal rats

Abstract Background Surfactant therapy is a standard of care for preterm infants with respiratory distress and reduces the incidence of death and bronchopulmonary dysplasia in these patients. Our previous study found that mesenchymal stem cells (MSCs) attenuated hyperoxia-induced lung injury and the...

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Bibliographic Details
Main Authors: Hsiu-Chu Chou, Chien-Hsiang Chang, Chien-Han Chen, Willie Lin, Chung-Ming Chen
Format: Article
Language:English
Published: BMC 2021-05-01
Series:Stem Cell Research & Therapy
Subjects:
Hyperoxia
Surfactant
Human umbilical cord-derived mesenchymal stem cells
Mean linear intercept
Vascular endothelial growth factor
Online Access:https://doi.org/10.1186/s13287-021-02335-4

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