HPV DNA/RNA detection in various oral and oropharyngeal biomaterials identifies active HPV infections also in non-neoplastic tonsils

HPV DNA/RNA detection in various oral and oropharyngeal biomaterials identifies active HPV infections also in non-neoplastic tonsils

Previous studies describe a correlation between HPV-positivity and non-smoking in TSCC; p16INK4A-expression as surrogate-marker for HPV-DNA/RNA-positivity is discussed controversially. In the present study, these parameters are assessed prospectively. HPV-status of sputum and tonsillar-swabs was ana...

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Bibliographic Details
Main Authors: Elgar Susanne Quabius, Silke Tribius, Alessa Heinrichs, Dirk Haaser, André Kühnel, Martin Laudien, Florian Hoppe, Robert Mlynski, Petra Ambrosch, Markus Hoffmann
Format: Article
Language:English
Published: Elsevier 2021-02-01
Series:Translational Oncology
Subjects:
Tissue
Gargle
Swabs sputum
HPV
TSCC
Tonsils
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523320304940

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