Dexmedetomidine alleviates TNF-α-induced injury of human neuroblastoma cell line SH-SY5Y through activating AMPK

Dexmedetomidine alleviates TNF-α-induced injury of human neuroblastoma cell line SH-SY5Y through activating AMPK

Objective To study the effect of dexmedetomidine (DEX) on TNF-α-induced injury of human neuroblastoma cell line SH-SY5Y and its mechanism. Methods CCK8 assay was used to detect cell activity and determine the optimal dose of DEX and TNF-α. The cells were divided into control group, model group, DEX...

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Bibliographic Details
Main Author: MU Yang, YANG Zhiwen
Format: Article
Language:zho
Published: Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College. 2024-02-01
Series:Jichu yixue yu linchuang
Subjects:
dexmedetomidine|oxidative stress|adenylate activates protein kinase (ampk)
Online Access:http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/1001-6325-2024-44-2-147.pdf

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