2-Deoxyglucose-Modified Folate Derivative: Self-Assembling Nanoparticle Able to Load Cisplatin

2-Deoxyglucose-Modified Folate Derivative: Self-Assembling Nanoparticle Able to Load Cisplatin

Folic acid has been widely introduced into nano-drug delivery systems to give nanoparticle-targeted characteristics. However, the poor water solubility of folic acid may hinder the exploitation of its ability to load antineoplastic drugs. In the present study, we designed a new folate derivative (FA...

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Bibliographic Details
Main Authors: Shaoming Jin, Zhongyao Du, Pengjie Wang, Huiyuan Guo, Hao Zhang, Xingen Lei, Fazheng Ren
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:Molecules
Subjects:
folic acid
2-Deoxyglucose
drug delivery system
cisplatin
self-assembly
Online Access:http://www.mdpi.com/1420-3049/24/6/1084

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