Robust identification of regulatory variants (eQTLs) using a differential expression framework developed for RNA-sequencing

Robust identification of regulatory variants (eQTLs) using a differential expression framework developed for RNA-sequencing

Abstract Background A gap currently exists between genetic variants and the underlying cell and tissue biology of a trait, and expression quantitative trait loci (eQTL) studies provide important information to help close that gap. However, two concerns that arise with eQTL analyses using RNA-sequenc...

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Bibliographic Details
Main Authors: Mackenzie A. Marrella, Fernando H. Biase
Format: Article
Language:English
Published: BMC 2023-05-01
Series:Journal of Animal Science and Biotechnology
Subjects:
Differential gene expression
eQTL analysis
Gene expression
RNA-sequencing
Single nucleotide polymorphism
Online Access:https://doi.org/10.1186/s40104-023-00861-0

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