Interleukin-4 affects microglial autophagic flux

Interleukin-4 affects microglial autophagic flux

Interleukin-4 plays an important protective role in Alzheimer’s disease by regulating microglial phenotype, phagocytosis of amyloid-β, and secretion of anti-inflammatory and neurotrophic cytokines. Recently, increasing evidence has suggested that autophagy regulates innate immunity by affecting M1/M...

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Bibliographic Details
Main Authors: Run-Hong Tang, Rui-Qun Qi, Hua-Yan Liu
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2019-01-01
Series:Neural Regeneration Research
Subjects:
nerve regeneration; Alzheimer′s disease; interleukin-4; amyloid-β; microglial autophagy; microglial polarization; microglia; M1 phenotype; M2 phenotype; peptide degradation; neural regeneration
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2019;volume=14;issue=9;spage=1594;epage=1602;aulast=Tang

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