Slowing the Progression of Myopia in Children with the MiSight Contact Lens: A Narrative Review of the Evidence

Abstract Myopia has become a major public health problem in the world due to the increase in its prevalence in the past few decades and due to sight-threatening pathologies associated with high myopia such as cataracts, glaucoma and especially myopic maculopathy. This article is a narrative review o...

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Main Authors: Alicia Ruiz-Pomeda, César Villa-Collar
Format: Article
Language:English
Published: Adis, Springer Healthcare 2020-09-01
Series:Ophthalmology and Therapy
Subjects:
Online Access:https://doi.org/10.1007/s40123-020-00298-y
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author Alicia Ruiz-Pomeda
César Villa-Collar
author_facet Alicia Ruiz-Pomeda
César Villa-Collar
author_sort Alicia Ruiz-Pomeda
collection DOAJ
description Abstract Myopia has become a major public health problem in the world due to the increase in its prevalence in the past few decades and due to sight-threatening pathologies associated with high myopia such as cataracts, glaucoma and especially myopic maculopathy. This article is a narrative review of the evidence that currently exists on a contact lenses (CLs) specifically designed to correct myopia and to slow its progression. To contextualise the topic we discuss the different classifications and definitions that have been used for myopia, the current burden of being myopic, and current treatment options to prevent and control its progression. There is evidence that exposure to sunlight reduces the risk of myopia onset and pharmacological treatment with atropine has been shown to be the most effective therapy for controlling its progression, followed by optical interventions such as CL fitting (orthokeratology or CLs specific for myopia control) designed to decrease retinal peripheral hyperopic defocus that seems to be the theory that suggests that axial elongation is driven by this defocus and explains why the eye continues to grow abnormally after emmetropisation and generates myopia. We will especially focus on MiSight CLs. MiSight is a daily replacement soft contact lens that has been clinically proven and approved by the US Food and Drug Administration (FDA) to control the progression of myopia in children. We analyse the optical design of MiSight CLs, as well as the results of the different efficacy and safety studies that led to the approval of the lens by the FDA. We also expose current knowledge gaps, limitations and future directions.
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spelling doaj.art-1c8c8027f66d40f0951e2e021afdfbf72022-12-21T22:12:54ZengAdis, Springer HealthcareOphthalmology and Therapy2193-82452193-65282020-09-019478379510.1007/s40123-020-00298-ySlowing the Progression of Myopia in Children with the MiSight Contact Lens: A Narrative Review of the EvidenceAlicia Ruiz-Pomeda0César Villa-Collar1Department of Ophthalmology, Hospital Universitario de MostolesDepartment of Pharmacy, Biotechnology, Nutrition and Optics and Optometry, Universidad Europea de MadridAbstract Myopia has become a major public health problem in the world due to the increase in its prevalence in the past few decades and due to sight-threatening pathologies associated with high myopia such as cataracts, glaucoma and especially myopic maculopathy. This article is a narrative review of the evidence that currently exists on a contact lenses (CLs) specifically designed to correct myopia and to slow its progression. To contextualise the topic we discuss the different classifications and definitions that have been used for myopia, the current burden of being myopic, and current treatment options to prevent and control its progression. There is evidence that exposure to sunlight reduces the risk of myopia onset and pharmacological treatment with atropine has been shown to be the most effective therapy for controlling its progression, followed by optical interventions such as CL fitting (orthokeratology or CLs specific for myopia control) designed to decrease retinal peripheral hyperopic defocus that seems to be the theory that suggests that axial elongation is driven by this defocus and explains why the eye continues to grow abnormally after emmetropisation and generates myopia. We will especially focus on MiSight CLs. MiSight is a daily replacement soft contact lens that has been clinically proven and approved by the US Food and Drug Administration (FDA) to control the progression of myopia in children. We analyse the optical design of MiSight CLs, as well as the results of the different efficacy and safety studies that led to the approval of the lens by the FDA. We also expose current knowledge gaps, limitations and future directions.https://doi.org/10.1007/s40123-020-00298-yMiSight contact lensMyopia controlSoft contact lens for myopia control
spellingShingle Alicia Ruiz-Pomeda
César Villa-Collar
Slowing the Progression of Myopia in Children with the MiSight Contact Lens: A Narrative Review of the Evidence
Ophthalmology and Therapy
MiSight contact lens
Myopia control
Soft contact lens for myopia control
title Slowing the Progression of Myopia in Children with the MiSight Contact Lens: A Narrative Review of the Evidence
title_full Slowing the Progression of Myopia in Children with the MiSight Contact Lens: A Narrative Review of the Evidence
title_fullStr Slowing the Progression of Myopia in Children with the MiSight Contact Lens: A Narrative Review of the Evidence
title_full_unstemmed Slowing the Progression of Myopia in Children with the MiSight Contact Lens: A Narrative Review of the Evidence
title_short Slowing the Progression of Myopia in Children with the MiSight Contact Lens: A Narrative Review of the Evidence
title_sort slowing the progression of myopia in children with the misight contact lens a narrative review of the evidence
topic MiSight contact lens
Myopia control
Soft contact lens for myopia control
url https://doi.org/10.1007/s40123-020-00298-y
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