Transcranial direct current stimulation in patients with Alzheimer’s disease: Challenges and responses
The use of transcranial direct current stimulation (tDCS) as a noninvasive therapeutic approach for Alzheimer’s disease (AD) has gained increasing attention. Research regarding the utility of tDCS in AD is inconsistent. In this study, we reviewed the importance of individual diversity among AD patie...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
International Association of Physical Chemists (IAPC)
2015-09-01
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| Series: | ADMET and DMPK |
| Online Access: | http://pub.iapchem.org/ojs/index.php/admet/article/view/199 |
| _version_ | 1811193207186259968 |
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| author | Hong Yuan Serik Tabarak Jing Yu Xu Lei |
| author_facet | Hong Yuan Serik Tabarak Jing Yu Xu Lei |
| author_sort | Hong Yuan |
| collection | DOAJ |
| description | The use of transcranial direct current stimulation (tDCS) as a noninvasive therapeutic approach for Alzheimer’s disease (AD) has gained increasing attention. Research regarding the utility of tDCS in AD is inconsistent. In this study, we reviewed the importance of individual diversity among AD patients, starting from the uninformative mean results. We also demonstrated variation among AD patients. Highly educated patients seem to benefit more; education also seems to modulate baseline measurements and the results. Individual cortical morphology also affects the current distribution, which influences the effectiveness of stimulation. We suggest the use of structural MRI to distinguish inter-individual variability; high-resolution modeling can also be used to predict current distributions and should be combined with cognitive training (CT) along with tDCS. |
| first_indexed | 2024-04-12T00:04:40Z |
| format | Article |
| id | doaj.art-1c8ca8d329f146a5ba1651772e05ad5b |
| institution | Directory Open Access Journal |
| issn | 1848-7718 |
| language | English |
| last_indexed | 2024-04-12T00:04:40Z |
| publishDate | 2015-09-01 |
| publisher | International Association of Physical Chemists (IAPC) |
| record_format | Article |
| series | ADMET and DMPK |
| spelling | doaj.art-1c8ca8d329f146a5ba1651772e05ad5b2022-12-22T03:56:07ZengInternational Association of Physical Chemists (IAPC)ADMET and DMPK1848-77182015-09-013323524110.5599/admet.3.3.199151Transcranial direct current stimulation in patients with Alzheimer’s disease: Challenges and responsesHong Yuan0Serik TabarakJing YuXu LeiSouthwest UniversityThe use of transcranial direct current stimulation (tDCS) as a noninvasive therapeutic approach for Alzheimer’s disease (AD) has gained increasing attention. Research regarding the utility of tDCS in AD is inconsistent. In this study, we reviewed the importance of individual diversity among AD patients, starting from the uninformative mean results. We also demonstrated variation among AD patients. Highly educated patients seem to benefit more; education also seems to modulate baseline measurements and the results. Individual cortical morphology also affects the current distribution, which influences the effectiveness of stimulation. We suggest the use of structural MRI to distinguish inter-individual variability; high-resolution modeling can also be used to predict current distributions and should be combined with cognitive training (CT) along with tDCS.http://pub.iapchem.org/ojs/index.php/admet/article/view/199 |
| spellingShingle | Hong Yuan Serik Tabarak Jing Yu Xu Lei Transcranial direct current stimulation in patients with Alzheimer’s disease: Challenges and responses ADMET and DMPK |
| title | Transcranial direct current stimulation in patients with Alzheimer’s disease: Challenges and responses |
| title_full | Transcranial direct current stimulation in patients with Alzheimer’s disease: Challenges and responses |
| title_fullStr | Transcranial direct current stimulation in patients with Alzheimer’s disease: Challenges and responses |
| title_full_unstemmed | Transcranial direct current stimulation in patients with Alzheimer’s disease: Challenges and responses |
| title_short | Transcranial direct current stimulation in patients with Alzheimer’s disease: Challenges and responses |
| title_sort | transcranial direct current stimulation in patients with alzheimer s disease challenges and responses |
| url | http://pub.iapchem.org/ojs/index.php/admet/article/view/199 |
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