Wnt/β-Catenin Signaling and Immunotherapy Resistance: Lessons for the Treatment of Urothelial Carcinoma

Wnt/β-Catenin Signaling and Immunotherapy Resistance: Lessons for the Treatment of Urothelial Carcinoma

Urothelial cell carcinoma (UCC) is a significant public health burden. It accounts for approximately 90 percent of all bladder cancers with an estimated 200,000 annual deaths globally. Platinum based cytotoxic chemotherapy combinations are the current standard of care in the frontline setting for me...

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Bibliographic Details
Main Authors: Alexander Chehrazi-Raffle, Tanya B. Dorff, Sumanta K. Pal, Yung Lyou
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Cancers
Subjects:
Wnt
β-catenin
urothelial cancer
immune checkpoint inhibitor
immunotherapy resistance
Online Access:https://www.mdpi.com/2072-6694/13/4/889

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