Trends in Epithelial Cell Abnormalities Observed on Cervical Smears over a 21-Year Period in a Tertiary Care Hospital in Kuwait
Objectives: This study aimed to analyse trends in epithelial cell abnormalities (ECAs) in cervical cytology at a tertiary care hospital in Kuwait. Methods: ECAs in 135,766 reports were compared over three seven-year periods between 1992 and 2012. Conventional Papanicolaou (Pap) smear tests were used...
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| Format: | Article |
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Sultan Qaboos University
2015-02-01
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| Series: | Sultan Qaboos University Medical Journal |
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| Online Access: | https://journals.squ.edu.om/index.php/squmj/article/view/1998 |
| _version_ | 1818645620671381504 |
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| author | Kusum Kapila Prem N. Sharma Sara S. George Azza Al-Shaheen Ahlam Al-Juwaiser Rana Al-Awadhi |
| author_facet | Kusum Kapila Prem N. Sharma Sara S. George Azza Al-Shaheen Ahlam Al-Juwaiser Rana Al-Awadhi |
| author_sort | Kusum Kapila |
| collection | DOAJ |
| description | Objectives: This study aimed to analyse trends in epithelial cell abnormalities (ECAs) in cervical cytology at a tertiary care hospital in Kuwait. Methods: ECAs in 135,766 reports were compared over three seven-year periods between 1992 and 2012. Conventional Papanicolaou (Pap) smear tests were used in the first two periods and ThinPrep (Hologic Corp., Bedford, Massachusetts, USA) tests were used in the third. Results: Significant increases in satisfactory smears, atypical squamous cells of undetermined significance (ASCUS) and atypical glandular cells of undetermined significance/atypical glandular cells (AGUS/AGCs) were seen in the second and third periods (P <0.001). No significant increases were observed among low-grade squamous intraepithelial lesions (LSILs) or high-grade squamous intraepithelial lesions (HSILs) (P >0.05). An increase was noted in carcinomas between the first and second periods although a significant decline was seen in the third (P <0.014). Conclusion: Satisfactory smears, ASCUS and AGUS/AGC increased during the study period although no significant increases in LSILs, HSILs or carcinomas were observed. |
| first_indexed | 2024-12-17T00:33:39Z |
| format | Article |
| id | doaj.art-1c8e9a4bce2b4b7ea779b71e54974a94 |
| institution | Directory Open Access Journal |
| issn | 2075-051X 2075-0528 |
| language | English |
| last_indexed | 2024-12-17T00:33:39Z |
| publishDate | 2015-02-01 |
| publisher | Sultan Qaboos University |
| record_format | Article |
| series | Sultan Qaboos University Medical Journal |
| spelling | doaj.art-1c8e9a4bce2b4b7ea779b71e54974a942022-12-21T22:10:12ZengSultan Qaboos UniversitySultan Qaboos University Medical Journal2075-051X2075-05282015-02-011511121151919Trends in Epithelial Cell Abnormalities Observed on Cervical Smears over a 21-Year Period in a Tertiary Care Hospital in KuwaitKusum Kapila0Prem N. Sharma1Sara S. George2Azza Al-Shaheen3Ahlam Al-Juwaiser4Rana Al-Awadhi5Department of Pathology, Kuwait University, Safat, KuwaitDepartment Health Science Centre, Faculty of Medicine, Kuwait University, Safat, KuwaitDepartment of Pathology, Kuwait University, Safat, KuwaitCytopathology Laboratory, Mubarak Al-Kabeer Hospital, Safat, KuwaitCytopathology Laboratory, Mubarak Al-Kabeer Hospital, Safat, KuwaitFaculty of Allied Health Sciences & Nursing, Kuwait University, Safat, KuwaitObjectives: This study aimed to analyse trends in epithelial cell abnormalities (ECAs) in cervical cytology at a tertiary care hospital in Kuwait. Methods: ECAs in 135,766 reports were compared over three seven-year periods between 1992 and 2012. Conventional Papanicolaou (Pap) smear tests were used in the first two periods and ThinPrep (Hologic Corp., Bedford, Massachusetts, USA) tests were used in the third. Results: Significant increases in satisfactory smears, atypical squamous cells of undetermined significance (ASCUS) and atypical glandular cells of undetermined significance/atypical glandular cells (AGUS/AGCs) were seen in the second and third periods (P <0.001). No significant increases were observed among low-grade squamous intraepithelial lesions (LSILs) or high-grade squamous intraepithelial lesions (HSILs) (P >0.05). An increase was noted in carcinomas between the first and second periods although a significant decline was seen in the third (P <0.014). Conclusion: Satisfactory smears, ASCUS and AGUS/AGC increased during the study period although no significant increases in LSILs, HSILs or carcinomas were observed.https://journals.squ.edu.om/index.php/squmj/article/view/1998cytological techniquespapanicolaou smearepithelial cellsretrospective studykuwait |
| spellingShingle | Kusum Kapila Prem N. Sharma Sara S. George Azza Al-Shaheen Ahlam Al-Juwaiser Rana Al-Awadhi Trends in Epithelial Cell Abnormalities Observed on Cervical Smears over a 21-Year Period in a Tertiary Care Hospital in Kuwait Sultan Qaboos University Medical Journal cytological techniques papanicolaou smear epithelial cells retrospective study kuwait |
| title | Trends in Epithelial Cell Abnormalities Observed on Cervical Smears over a 21-Year Period in a Tertiary Care Hospital in Kuwait |
| title_full | Trends in Epithelial Cell Abnormalities Observed on Cervical Smears over a 21-Year Period in a Tertiary Care Hospital in Kuwait |
| title_fullStr | Trends in Epithelial Cell Abnormalities Observed on Cervical Smears over a 21-Year Period in a Tertiary Care Hospital in Kuwait |
| title_full_unstemmed | Trends in Epithelial Cell Abnormalities Observed on Cervical Smears over a 21-Year Period in a Tertiary Care Hospital in Kuwait |
| title_short | Trends in Epithelial Cell Abnormalities Observed on Cervical Smears over a 21-Year Period in a Tertiary Care Hospital in Kuwait |
| title_sort | trends in epithelial cell abnormalities observed on cervical smears over a 21 year period in a tertiary care hospital in kuwait |
| topic | cytological techniques papanicolaou smear epithelial cells retrospective study kuwait |
| url | https://journals.squ.edu.om/index.php/squmj/article/view/1998 |
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