Liver Stiffness Values to Predict Occurrence and Recurrence of Hepatocellular Carcinoma
Globally, liver cancer is the third most frequent etiology of cancer death, with the rates of occurrence of both new cases and mortality estimated to increase. Given the availability of multiple treatments, interdisciplinary management of the patient is crucial. Moreover, the diagnostic assessment o...
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| Format: | Article |
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MDPI AG
2024-03-01
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| Series: | Life |
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| Online Access: | https://www.mdpi.com/2075-1729/14/3/342 |
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| author | Cristina Stasi Stefano Brillanti |
| author_facet | Cristina Stasi Stefano Brillanti |
| author_sort | Cristina Stasi |
| collection | DOAJ |
| description | Globally, liver cancer is the third most frequent etiology of cancer death, with the rates of occurrence of both new cases and mortality estimated to increase. Given the availability of multiple treatments, interdisciplinary management of the patient is crucial. Moreover, the diagnostic assessment of patients with severe liver fibrosis is essential for the staging of HCC and liver cirrhosis and early diagnosis of HCC. In this context, non-invasive evaluation plays a critical role in identifying prognostic factors of clinical application for the surveillance of the occurrence or recurrence of HCC. The new frontiers of transient elastography have become a useful tool to assess the risk of HCC occurrence and recurrence. There has been a major increase in studies investigating the cutoff liver stiffness value that best predicts the need for monitoring for the onset of HCC. Therefore, this review discusses the new advances that have occurred in the last four years on HCC, highlighting the new frontiers of non-invasive evaluation of HCC subjects, with particular attention regarding the clinical application of liver stiffness assessment for de novo HCC and predicting recurrence in patients with chronic HCV achieving sustained virological response after treatment with direct antiviral agents. |
| first_indexed | 2024-04-24T18:04:28Z |
| format | Article |
| id | doaj.art-1c948747c74c43e5880bfa2e6b431845 |
| institution | Directory Open Access Journal |
| issn | 2075-1729 |
| language | English |
| last_indexed | 2024-04-24T18:04:28Z |
| publishDate | 2024-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Life |
| spelling | doaj.art-1c948747c74c43e5880bfa2e6b4318452024-03-27T13:51:11ZengMDPI AGLife2075-17292024-03-0114334210.3390/life14030342Liver Stiffness Values to Predict Occurrence and Recurrence of Hepatocellular CarcinomaCristina Stasi0Stefano Brillanti1Department of Medical, Surgical and Neuroscience Sciences, University of Siena, 53100 Siena, ItalyDepartment of Medical, Surgical and Neuroscience Sciences, University of Siena, 53100 Siena, ItalyGlobally, liver cancer is the third most frequent etiology of cancer death, with the rates of occurrence of both new cases and mortality estimated to increase. Given the availability of multiple treatments, interdisciplinary management of the patient is crucial. Moreover, the diagnostic assessment of patients with severe liver fibrosis is essential for the staging of HCC and liver cirrhosis and early diagnosis of HCC. In this context, non-invasive evaluation plays a critical role in identifying prognostic factors of clinical application for the surveillance of the occurrence or recurrence of HCC. The new frontiers of transient elastography have become a useful tool to assess the risk of HCC occurrence and recurrence. There has been a major increase in studies investigating the cutoff liver stiffness value that best predicts the need for monitoring for the onset of HCC. Therefore, this review discusses the new advances that have occurred in the last four years on HCC, highlighting the new frontiers of non-invasive evaluation of HCC subjects, with particular attention regarding the clinical application of liver stiffness assessment for de novo HCC and predicting recurrence in patients with chronic HCV achieving sustained virological response after treatment with direct antiviral agents.https://www.mdpi.com/2075-1729/14/3/342tumor microenvironmentshepatocellular carcinomaliver stiffnesscutoffsHCC occurrencerecurrence |
| spellingShingle | Cristina Stasi Stefano Brillanti Liver Stiffness Values to Predict Occurrence and Recurrence of Hepatocellular Carcinoma Life tumor microenvironments hepatocellular carcinoma liver stiffness cutoffs HCC occurrence recurrence |
| title | Liver Stiffness Values to Predict Occurrence and Recurrence of Hepatocellular Carcinoma |
| title_full | Liver Stiffness Values to Predict Occurrence and Recurrence of Hepatocellular Carcinoma |
| title_fullStr | Liver Stiffness Values to Predict Occurrence and Recurrence of Hepatocellular Carcinoma |
| title_full_unstemmed | Liver Stiffness Values to Predict Occurrence and Recurrence of Hepatocellular Carcinoma |
| title_short | Liver Stiffness Values to Predict Occurrence and Recurrence of Hepatocellular Carcinoma |
| title_sort | liver stiffness values to predict occurrence and recurrence of hepatocellular carcinoma |
| topic | tumor microenvironments hepatocellular carcinoma liver stiffness cutoffs HCC occurrence recurrence |
| url | https://www.mdpi.com/2075-1729/14/3/342 |
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