Vascular control of the Drosophila haematopoietic microenvironment by Slit/Robo signalling
The posterior signalling centre (PSC) in Drosophilalarva regulates blood cell differentiation but it is unclear how this is controlled. Here, the authors show that Slit/Robo signalling from the vascular system regulates PSC morphology and function, in turn, regulating blood cell differentiation.
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
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Nature Portfolio
2016-05-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/ncomms11634 |
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author | Ismaël Morin-Poulard Anurag Sharma Isabelle Louradour Nathalie Vanzo Alain Vincent Michèle Crozatier |
author_facet | Ismaël Morin-Poulard Anurag Sharma Isabelle Louradour Nathalie Vanzo Alain Vincent Michèle Crozatier |
author_sort | Ismaël Morin-Poulard |
collection | DOAJ |
description | The posterior signalling centre (PSC) in Drosophilalarva regulates blood cell differentiation but it is unclear how this is controlled. Here, the authors show that Slit/Robo signalling from the vascular system regulates PSC morphology and function, in turn, regulating blood cell differentiation. |
first_indexed | 2024-12-20T21:34:30Z |
format | Article |
id | doaj.art-1c95b05837744bfb878843dce508918f |
institution | Directory Open Access Journal |
issn | 2041-1723 |
language | English |
last_indexed | 2024-12-20T21:34:30Z |
publishDate | 2016-05-01 |
publisher | Nature Portfolio |
record_format | Article |
series | Nature Communications |
spelling | doaj.art-1c95b05837744bfb878843dce508918f2022-12-21T19:25:59ZengNature PortfolioNature Communications2041-17232016-05-017111210.1038/ncomms11634Vascular control of the Drosophila haematopoietic microenvironment by Slit/Robo signallingIsmaël Morin-Poulard0Anurag Sharma1Isabelle Louradour2Nathalie Vanzo3Alain Vincent4Michèle Crozatier5Centre de Biologie du Développement, UMR 5547 CNRS/Université Toulouse III and Fédération de Recherche de Biologie de ToulouseCentre de Biologie du Développement, UMR 5547 CNRS/Université Toulouse III and Fédération de Recherche de Biologie de ToulouseCentre de Biologie du Développement, UMR 5547 CNRS/Université Toulouse III and Fédération de Recherche de Biologie de ToulouseCentre de Biologie du Développement, UMR 5547 CNRS/Université Toulouse III and Fédération de Recherche de Biologie de ToulouseCentre de Biologie du Développement, UMR 5547 CNRS/Université Toulouse III and Fédération de Recherche de Biologie de ToulouseCentre de Biologie du Développement, UMR 5547 CNRS/Université Toulouse III and Fédération de Recherche de Biologie de ToulouseThe posterior signalling centre (PSC) in Drosophilalarva regulates blood cell differentiation but it is unclear how this is controlled. Here, the authors show that Slit/Robo signalling from the vascular system regulates PSC morphology and function, in turn, regulating blood cell differentiation.https://doi.org/10.1038/ncomms11634 |
spellingShingle | Ismaël Morin-Poulard Anurag Sharma Isabelle Louradour Nathalie Vanzo Alain Vincent Michèle Crozatier Vascular control of the Drosophila haematopoietic microenvironment by Slit/Robo signalling Nature Communications |
title | Vascular control of the Drosophila haematopoietic microenvironment by Slit/Robo signalling |
title_full | Vascular control of the Drosophila haematopoietic microenvironment by Slit/Robo signalling |
title_fullStr | Vascular control of the Drosophila haematopoietic microenvironment by Slit/Robo signalling |
title_full_unstemmed | Vascular control of the Drosophila haematopoietic microenvironment by Slit/Robo signalling |
title_short | Vascular control of the Drosophila haematopoietic microenvironment by Slit/Robo signalling |
title_sort | vascular control of the drosophila haematopoietic microenvironment by slit robo signalling |
url | https://doi.org/10.1038/ncomms11634 |
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