Diamagnetic Therapy in a Patient with Complex Regional Pain Syndrome Type I and Multiple Drug Intolerance: A Case Report

Complex regional pain syndrome (CRPS) is a neurologic chronic pain condition hard to diagnose and treat, and able to significantly impact the quality of life. Currently, the available multimodal, individualized treatments (i.e., pharmacological and non-pharmacological therapies including invasive pr...

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Main Authors: Roberta Roberti, Gianmarco Marcianò, Alessandro Casarella, Vincenzo Rania, Caterina Palleria, Cristina Vocca, Luca Catarisano, Lucia Muraca, Rita Citraro, Pietro Romeo, Giovambattista De Sarro, Luca Gallelli
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Reports
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Online Access:https://www.mdpi.com/2571-841X/5/2/18
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author Roberta Roberti
Gianmarco Marcianò
Alessandro Casarella
Vincenzo Rania
Caterina Palleria
Cristina Vocca
Luca Catarisano
Lucia Muraca
Rita Citraro
Pietro Romeo
Giovambattista De Sarro
Luca Gallelli
author_facet Roberta Roberti
Gianmarco Marcianò
Alessandro Casarella
Vincenzo Rania
Caterina Palleria
Cristina Vocca
Luca Catarisano
Lucia Muraca
Rita Citraro
Pietro Romeo
Giovambattista De Sarro
Luca Gallelli
author_sort Roberta Roberti
collection DOAJ
description Complex regional pain syndrome (CRPS) is a neurologic chronic pain condition hard to diagnose and treat, and able to significantly impact the quality of life. Currently, the available multimodal, individualized treatments (i.e., pharmacological and non-pharmacological therapies including invasive procedures) are aimed only at symptom control. Herein, we report a 69-year-old Caucasian female who came to our attention due to a 3-year history of severe (10/10) burning pain in her right ankle, along with oedema and local changes in skin color and temperature, which occurred after the ankle sprain. Previous pharmacological attempts failed due to multiple drug intolerance. Clinical examination confirmed the CRPS type I diagnosis, and a weekly diamagnetic therapy protocol was started since the patient refused further medications and interventional procedures. After 10 weeks of treatment, a significant (<i>p</i> < 0.01) reduction in pain severity and absence of oedema (difference in ankles’ circumference: from 3 cm to 0) were observed, with consequent improvements in quality of life and no adverse events. Although high-quality clinical evidence is still lacking, our case report suggests further investigating the potential use of diamagnetic therapy as a non-invasive and safe adjunctive treatment for CRPS, and as an alternative when patients did not benefit from drugs and/or refuse invasive procedures.
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spelling doaj.art-1c9b954a726c4ec1bd6854ed24e89d872023-11-23T18:49:34ZengMDPI AGReports2571-841X2022-05-01521810.3390/reports5020018Diamagnetic Therapy in a Patient with Complex Regional Pain Syndrome Type I and Multiple Drug Intolerance: A Case ReportRoberta Roberti0Gianmarco Marcianò1Alessandro Casarella2Vincenzo Rania3Caterina Palleria4Cristina Vocca5Luca Catarisano6Lucia Muraca7Rita Citraro8Pietro Romeo9Giovambattista De Sarro10Luca Gallelli11Department of Health Science, School of Medicine, University of Catanzaro, 88100 Catanzaro, ItalyDepartment of Health Science, School of Medicine, University of Catanzaro, 88100 Catanzaro, ItalyDepartment of Health Science, School of Medicine, University of Catanzaro, 88100 Catanzaro, ItalyDepartment of Health Science, School of Medicine, University of Catanzaro, 88100 Catanzaro, ItalyOperative Unit of Clinical Pharmacology and Pharmacovigilance, Mater Domini Hospital, 88100 Catanzaro, ItalyDepartment of Health Science, School of Medicine, University of Catanzaro, 88100 Catanzaro, ItalyDepartment of Health Science, School of Medicine, University of Catanzaro, 88100 Catanzaro, ItalyDepartment of Health Science, School of Medicine, University of Catanzaro, 88100 Catanzaro, ItalyDepartment of Health Science, School of Medicine, University of Catanzaro, 88100 Catanzaro, ItalyDepartment of Orthopedics, IRCCS Istituto Ortopedico Galeazzi, 20123 Milan, ItalyDepartment of Health Science, School of Medicine, University of Catanzaro, 88100 Catanzaro, ItalyDepartment of Health Science, School of Medicine, University of Catanzaro, 88100 Catanzaro, ItalyComplex regional pain syndrome (CRPS) is a neurologic chronic pain condition hard to diagnose and treat, and able to significantly impact the quality of life. Currently, the available multimodal, individualized treatments (i.e., pharmacological and non-pharmacological therapies including invasive procedures) are aimed only at symptom control. Herein, we report a 69-year-old Caucasian female who came to our attention due to a 3-year history of severe (10/10) burning pain in her right ankle, along with oedema and local changes in skin color and temperature, which occurred after the ankle sprain. Previous pharmacological attempts failed due to multiple drug intolerance. Clinical examination confirmed the CRPS type I diagnosis, and a weekly diamagnetic therapy protocol was started since the patient refused further medications and interventional procedures. After 10 weeks of treatment, a significant (<i>p</i> < 0.01) reduction in pain severity and absence of oedema (difference in ankles’ circumference: from 3 cm to 0) were observed, with consequent improvements in quality of life and no adverse events. Although high-quality clinical evidence is still lacking, our case report suggests further investigating the potential use of diamagnetic therapy as a non-invasive and safe adjunctive treatment for CRPS, and as an alternative when patients did not benefit from drugs and/or refuse invasive procedures.https://www.mdpi.com/2571-841X/5/2/18algodystrophyCRPSdrug intolerancemagnetic fieldsPEMFsphysical therapy
spellingShingle Roberta Roberti
Gianmarco Marcianò
Alessandro Casarella
Vincenzo Rania
Caterina Palleria
Cristina Vocca
Luca Catarisano
Lucia Muraca
Rita Citraro
Pietro Romeo
Giovambattista De Sarro
Luca Gallelli
Diamagnetic Therapy in a Patient with Complex Regional Pain Syndrome Type I and Multiple Drug Intolerance: A Case Report
Reports
algodystrophy
CRPS
drug intolerance
magnetic fields
PEMFs
physical therapy
title Diamagnetic Therapy in a Patient with Complex Regional Pain Syndrome Type I and Multiple Drug Intolerance: A Case Report
title_full Diamagnetic Therapy in a Patient with Complex Regional Pain Syndrome Type I and Multiple Drug Intolerance: A Case Report
title_fullStr Diamagnetic Therapy in a Patient with Complex Regional Pain Syndrome Type I and Multiple Drug Intolerance: A Case Report
title_full_unstemmed Diamagnetic Therapy in a Patient with Complex Regional Pain Syndrome Type I and Multiple Drug Intolerance: A Case Report
title_short Diamagnetic Therapy in a Patient with Complex Regional Pain Syndrome Type I and Multiple Drug Intolerance: A Case Report
title_sort diamagnetic therapy in a patient with complex regional pain syndrome type i and multiple drug intolerance a case report
topic algodystrophy
CRPS
drug intolerance
magnetic fields
PEMFs
physical therapy
url https://www.mdpi.com/2571-841X/5/2/18
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