Structural and Functional Changes of Reconstituted High-Density Lipoprotein (HDL) by Incorporation of α-synuclein: A Potent Antioxidant and Anti-Glycation Activity of α-synuclein and apoA-I in HDL at High Molar Ratio of α-synuclein

Structural and Functional Changes of Reconstituted High-Density Lipoprotein (HDL) by Incorporation of α-synuclein: A Potent Antioxidant and Anti-Glycation Activity of α-synuclein and apoA-I in HDL at High Molar Ratio of α-synuclein

α-synuclein (α-syn) is a major culprit of Parkinson’s disease (PD), although lipoprotein metabolism is very important in the pathogenesis of PD. α-syn was expressed and purified using the pET30a expression vector from an <i>E. coli</i> expression system to elucidate the physiological eff...

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Bibliographic Details
Main Author: Kyung-Hyun Cho
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Molecules
Subjects:
α-synuclein
apolipoprotein A-I
Parkinson’s disease
high-density lipoproteins
oxidation
glycation
Online Access:https://www.mdpi.com/1420-3049/26/24/7485

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