Serum Phosphate Level in Patients with Severe Acute Malnutrition at Nutrition Stabilization Centre, Children Hospital, and Institute of Child Health Multan

Objective: To evaluate the serum phosphate level of children with severe acute malnutrition and effect of therapeutic feeds (F75 and F100) on serum phosphate levels. Study Design: Prospective Observational Study. Place and Duration of Study : The study was conducted at Stabilization center of Chil...

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Main Authors: Saadia Khan, Reema Arshad, Saliha Gillani, Sundas Irshad, Tehseen Ikram, Nazia Batool
Format: Article
Language:English
Published: Riphah International University, Islamabad 2023-06-01
Series:Journal of Islamic International Medical College
Subjects:
Online Access:https://journals.riphah.edu.pk/index.php/jiimc/article/view/1647
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author Saadia Khan
Reema Arshad
Saliha Gillani
Sundas Irshad
Tehseen Ikram
Nazia Batool
author_facet Saadia Khan
Reema Arshad
Saliha Gillani
Sundas Irshad
Tehseen Ikram
Nazia Batool
author_sort Saadia Khan
collection DOAJ
description Objective: To evaluate the serum phosphate level of children with severe acute malnutrition and effect of therapeutic feeds (F75 and F100) on serum phosphate levels. Study Design: Prospective Observational Study. Place and Duration of Study : The study was conducted at Stabilization center of Children's Hospital and Institute of Child Health Multan from 1 March 2018 to 30 March 2019. Materials and Methods: The total 270 children with severe acute malnutrition, who were under 5 years of age and admitted to the stabilization center for complicated SAM during study duration were included in the study. Initial management of the patients were started by following WHO protocols for Severe Acute Malnutrition management and the baseline labs along with serum phosphate levels were sent for evaluation. Patients were admitted at Stabilization Centre for the management plan as per guidelines. Once the patients were stabilized in one week approximately the transition towards rehabilitation phase of severe acute management started. Serum phosphate levels were assessed at admission, at stabilization (day 7 of admission) and at the time of discharge. Data was analyzed using SPSS version 21. Results: The mean age of our patients was 22 ± 2 months. The male to female ratio were 1:2. Hypophosphatemia was documented in 180 (66%) patients with mean 0.96 ± 0.40 mmol/ltr < (1.45 –1.78mmol/ltr) serum phosphate levels at the time of admission. During transition phase the phosphate levels were 1.1± 0.45 mmol/l and after rehabilitation phase 1.45 ± 0.45 mmol/l on average of 15 days of management. After using F75 and F100 therapeutic feeds in stabilization, transition, and rehabilitation phase 178 (98.9%) children were treated and had normal serum phosphate level at the time of discharge. Conclusion: Hypophosphatemia is commonly present in SAM children. Introduction of therapeutic feeds F75 and F-100 during stabilization phase and rehabilitation phase significantly improves phosphate levels in SAM children with low phosphate levels.
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spelling doaj.art-1c9f51067c54448cbf5cc14db91850d62023-06-27T05:24:23ZengRiphah International University, IslamabadJournal of Islamic International Medical College1815-40182410-54222023-06-01182105108https://doi.org/10.57234/jiimc.june23.1647Serum Phosphate Level in Patients with Severe Acute Malnutrition at Nutrition Stabilization Centre, Children Hospital, and Institute of Child Health MultanSaadia Khan0Reema Arshad1Saliha Gillani2Sundas Irshad3Tehseen Ikram4Nazia Batool5Department of Preventive Pediatrics, Children’s Hospital and the Institute of Child Health, Multan.Department of Preventive Pediatrics, Children’s Hospital and the Institute of Child Health, Multan.Department of Pharmacology, Nishter Medical University, MultanDepartment of Preventive Pediatrics, Children’s Hospital and the Institute of Child Health, Multan.Department of Preventive Pediatrics, Children’s Hospital and the Institute of Child Health, MultanDepartment of Preventive Pediatrics, Children’s Hospital and the Institute of Child Health, Multan.Objective: To evaluate the serum phosphate level of children with severe acute malnutrition and effect of therapeutic feeds (F75 and F100) on serum phosphate levels. Study Design: Prospective Observational Study. Place and Duration of Study : The study was conducted at Stabilization center of Children's Hospital and Institute of Child Health Multan from 1 March 2018 to 30 March 2019. Materials and Methods: The total 270 children with severe acute malnutrition, who were under 5 years of age and admitted to the stabilization center for complicated SAM during study duration were included in the study. Initial management of the patients were started by following WHO protocols for Severe Acute Malnutrition management and the baseline labs along with serum phosphate levels were sent for evaluation. Patients were admitted at Stabilization Centre for the management plan as per guidelines. Once the patients were stabilized in one week approximately the transition towards rehabilitation phase of severe acute management started. Serum phosphate levels were assessed at admission, at stabilization (day 7 of admission) and at the time of discharge. Data was analyzed using SPSS version 21. Results: The mean age of our patients was 22 ± 2 months. The male to female ratio were 1:2. Hypophosphatemia was documented in 180 (66%) patients with mean 0.96 ± 0.40 mmol/ltr < (1.45 –1.78mmol/ltr) serum phosphate levels at the time of admission. During transition phase the phosphate levels were 1.1± 0.45 mmol/l and after rehabilitation phase 1.45 ± 0.45 mmol/l on average of 15 days of management. After using F75 and F100 therapeutic feeds in stabilization, transition, and rehabilitation phase 178 (98.9%) children were treated and had normal serum phosphate level at the time of discharge. Conclusion: Hypophosphatemia is commonly present in SAM children. Introduction of therapeutic feeds F75 and F-100 during stabilization phase and rehabilitation phase significantly improves phosphate levels in SAM children with low phosphate levels. https://journals.riphah.edu.pk/index.php/jiimc/article/view/1647hypophosphatemianutrition rehabilitationphosphoroussevere acute malnutritionserum phosphate levels
spellingShingle Saadia Khan
Reema Arshad
Saliha Gillani
Sundas Irshad
Tehseen Ikram
Nazia Batool
Serum Phosphate Level in Patients with Severe Acute Malnutrition at Nutrition Stabilization Centre, Children Hospital, and Institute of Child Health Multan
Journal of Islamic International Medical College
hypophosphatemia
nutrition rehabilitation
phosphorous
severe acute malnutrition
serum phosphate levels
title Serum Phosphate Level in Patients with Severe Acute Malnutrition at Nutrition Stabilization Centre, Children Hospital, and Institute of Child Health Multan
title_full Serum Phosphate Level in Patients with Severe Acute Malnutrition at Nutrition Stabilization Centre, Children Hospital, and Institute of Child Health Multan
title_fullStr Serum Phosphate Level in Patients with Severe Acute Malnutrition at Nutrition Stabilization Centre, Children Hospital, and Institute of Child Health Multan
title_full_unstemmed Serum Phosphate Level in Patients with Severe Acute Malnutrition at Nutrition Stabilization Centre, Children Hospital, and Institute of Child Health Multan
title_short Serum Phosphate Level in Patients with Severe Acute Malnutrition at Nutrition Stabilization Centre, Children Hospital, and Institute of Child Health Multan
title_sort serum phosphate level in patients with severe acute malnutrition at nutrition stabilization centre children hospital and institute of child health multan
topic hypophosphatemia
nutrition rehabilitation
phosphorous
severe acute malnutrition
serum phosphate levels
url https://journals.riphah.edu.pk/index.php/jiimc/article/view/1647
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