Acute Fingolimod Effects on Baroreflex and Cardiovascular Autonomic Control in Multiple Sclerosis

Acute Fingolimod Effects on Baroreflex and Cardiovascular Autonomic Control in Multiple Sclerosis

Background: Fingolimod, an oral drug used in multiple sclerosis (MS) treatment, exerts its action through S1P-receptor engagement. These receptors are also expressed in heart and endothelial cells. The engagement of receptors on the atrial heart myocytes may cause a slowing effect on heart rate (HR)...

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Bibliographic Details
Main Authors: Vittorio Racca, Marco Rovaris, Rosella Cavarretta, Emanuele Vaini, Anastasia Toccafondi, Marco Di Rienzo
Format: Article
Language:English
Published: SAGE Publishing 2019-05-01
Series:Journal of Central Nervous System Disease
Online Access:https://doi.org/10.1177/1179573519849945

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