Dietary Antioxidant Capacity Indices are Negatively Correlated to LDL-Oxidation in Adults
Introduction. Former research studies have demonstrated controversial associations between dietary indices and oxidative stress biomarkers including oxidized low-density lipoprotein (ox-LDL) and malondialdehyde (MDA). So, in this cross-sectional study, we aimed to assess the association of dietary t...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Hindawi-Wiley
2023-01-01
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| Series: | International Journal of Clinical Practice |
| Online Access: | http://dx.doi.org/10.1155/2023/5446163 |
| _version_ | 1797866957494550528 |
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| author | Mehran Nouri Mitra Soltani Milad Rajabzadeh-Dehkordi Nastaran Rafieipour Moein Askarpour Maryam Najafi Shiva Faghih |
| author_facet | Mehran Nouri Mitra Soltani Milad Rajabzadeh-Dehkordi Nastaran Rafieipour Moein Askarpour Maryam Najafi Shiva Faghih |
| author_sort | Mehran Nouri |
| collection | DOAJ |
| description | Introduction. Former research studies have demonstrated controversial associations between dietary indices and oxidative stress biomarkers including oxidized low-density lipoprotein (ox-LDL) and malondialdehyde (MDA). So, in this cross-sectional study, we aimed to assess the association of dietary total antioxidant capacity (DTAC), oxidative balance score, and phytochemical index (PI) with ox-LDL/MDA in a healthy adult population of Shiraz, Iran. Methods. 236 individuals participated in this cross-sectional study. DTAC, OBS, and PI were calculated using a 168-item food frequency questionnaire (FFQ), which was previously validated in Iran. We measured ox-LDL and MDA in blood samples of the participants using commercially existing kits. Crude and adjusted models of linear regression were used to evaluate the relation of dietary indices with ox-LDL and MDA. Results. There was a significant association between ox-LDL and DTAC in both crude (β = −1.55; 95% CI: −2.53, −0.58; P-trend = 0.002) and adjusted (β = −1.65 95% CI: −2.66, −0.64; P-trend = 0.001) models. Also, a negative association was observed between ox-LDL and PI in the crude (β = −1.26 95% CI: −2.33, −0.29; P-trend = 0.01) and adjusted (β = −1.36 95% CI: −2.38, −0.34; P-trend = 0.01) models. Conclusion. Results of this study showed that DTAC and PI were inversely associated with ox-LDL as markers of lipid peroxidation. But no correlations were seen between MDA and dietary antioxidant indices. |
| first_indexed | 2024-04-09T23:32:35Z |
| format | Article |
| id | doaj.art-1ca196223ebc461ab07f0992bb706bee |
| institution | Directory Open Access Journal |
| issn | 1742-1241 |
| language | English |
| last_indexed | 2024-04-09T23:32:35Z |
| publishDate | 2023-01-01 |
| publisher | Hindawi-Wiley |
| record_format | Article |
| series | International Journal of Clinical Practice |
| spelling | doaj.art-1ca196223ebc461ab07f0992bb706bee2023-03-21T00:00:06ZengHindawi-WileyInternational Journal of Clinical Practice1742-12412023-01-01202310.1155/2023/5446163Dietary Antioxidant Capacity Indices are Negatively Correlated to LDL-Oxidation in AdultsMehran Nouri0Mitra Soltani1Milad Rajabzadeh-Dehkordi2Nastaran Rafieipour3Moein Askarpour4Maryam Najafi5Shiva Faghih6Department of Community NutritionDepartment of Clinical NutritionDepartment of Community NutritionIslamic Azad UniversityDepartment of Clinical NutritionDepartment of Community NutritionDepartment of Community NutritionIntroduction. Former research studies have demonstrated controversial associations between dietary indices and oxidative stress biomarkers including oxidized low-density lipoprotein (ox-LDL) and malondialdehyde (MDA). So, in this cross-sectional study, we aimed to assess the association of dietary total antioxidant capacity (DTAC), oxidative balance score, and phytochemical index (PI) with ox-LDL/MDA in a healthy adult population of Shiraz, Iran. Methods. 236 individuals participated in this cross-sectional study. DTAC, OBS, and PI were calculated using a 168-item food frequency questionnaire (FFQ), which was previously validated in Iran. We measured ox-LDL and MDA in blood samples of the participants using commercially existing kits. Crude and adjusted models of linear regression were used to evaluate the relation of dietary indices with ox-LDL and MDA. Results. There was a significant association between ox-LDL and DTAC in both crude (β = −1.55; 95% CI: −2.53, −0.58; P-trend = 0.002) and adjusted (β = −1.65 95% CI: −2.66, −0.64; P-trend = 0.001) models. Also, a negative association was observed between ox-LDL and PI in the crude (β = −1.26 95% CI: −2.33, −0.29; P-trend = 0.01) and adjusted (β = −1.36 95% CI: −2.38, −0.34; P-trend = 0.01) models. Conclusion. Results of this study showed that DTAC and PI were inversely associated with ox-LDL as markers of lipid peroxidation. But no correlations were seen between MDA and dietary antioxidant indices.http://dx.doi.org/10.1155/2023/5446163 |
| spellingShingle | Mehran Nouri Mitra Soltani Milad Rajabzadeh-Dehkordi Nastaran Rafieipour Moein Askarpour Maryam Najafi Shiva Faghih Dietary Antioxidant Capacity Indices are Negatively Correlated to LDL-Oxidation in Adults International Journal of Clinical Practice |
| title | Dietary Antioxidant Capacity Indices are Negatively Correlated to LDL-Oxidation in Adults |
| title_full | Dietary Antioxidant Capacity Indices are Negatively Correlated to LDL-Oxidation in Adults |
| title_fullStr | Dietary Antioxidant Capacity Indices are Negatively Correlated to LDL-Oxidation in Adults |
| title_full_unstemmed | Dietary Antioxidant Capacity Indices are Negatively Correlated to LDL-Oxidation in Adults |
| title_short | Dietary Antioxidant Capacity Indices are Negatively Correlated to LDL-Oxidation in Adults |
| title_sort | dietary antioxidant capacity indices are negatively correlated to ldl oxidation in adults |
| url | http://dx.doi.org/10.1155/2023/5446163 |
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