Exploiting convergent phenotypes to derive a pan-cancer cisplatin response gene expression signature

Abstract Precision medicine offers remarkable potential for the treatment of cancer, but is largely focused on tumors that harbor actionable mutations. Gene expression signatures can expand the scope of precision medicine by predicting response to traditional (cytotoxic) chemotherapy agents without...

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Bibliographic Details
Main Authors: Jessica A. Scarborough, Steven A. Eschrich, Javier Torres-Roca, Andrew Dhawan, Jacob G. Scott
Format: Article
Language:English
Published: Nature Portfolio 2023-04-01
Series:npj Precision Oncology
Online Access:https://doi.org/10.1038/s41698-023-00375-y

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