Cobalt Chloride-induced Hypoxia Can Lead SKBR3 and HEK293T Cell Lines toward Epithelial-mesenchymal Transition

Cobalt Chloride-induced Hypoxia Can Lead SKBR3 and HEK293T Cell Lines toward Epithelial-mesenchymal Transition

Hypoxia is a common characteristic of the tumor microenvironment. In response to hypoxia, expression of the hypoxia-inducible factor (HIF) can lead to activation of downstream molecular events such as epithelial-mesenchymal transition (EMT), invasion, and angiogenesis. In this study, CoCl2 was used...

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Bibliographic Details
Main Authors: Maryam Sadri, Ali-Akbar Delbandi, Nesa Rashidi, Gholam Ali Kardar, Reza Falak
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2022-08-01
Series:Iranian Journal of Allergy, Asthma and Immunology
Subjects:
Cobaltous chloride
Epithelial-mesenchymal transition
Hypoxia
Hypoxia-inducible factor 1
Online Access:https://ijaai.tums.ac.ir/index.php/ijaai/article/view/3462

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