Is Weak Acid Beneficial for Addressing Checkpoint Inhibitor–Triggered Cancer Hyper Progression in Anti-PD1/PD-L1 Immunotherapies?

Numerous cases of checkpoint inhibitor–triggered cancer hyperprogression have been documented. A previous hypothesis attributes cancer onset to the local buildup of hydrogen chloride, jointly mediated by hydrogen bond donors and acceptors and basic amino acids. The anti-PD1/PD-L1 immunotherapies may...

Full description

Bibliographic Details
Main Authors: Yulin Wan MS, Shanshan An MS, Yanchao Zhou MS, Jiaming Zhang MS, Ying Zhang MS, Tao Gan PhD, Qiuyun Liu PhD
Format: Article
Language:English
Published: SAGE Publishing 2020-08-01
Series:Cancer Control
Online Access:https://doi.org/10.1177/1073274820944290