A physiological glucocorticoid rhythm is an important regulator of brown adipose tissue function

A physiological glucocorticoid rhythm is an important regulator of brown adipose tissue function

Objective: Brown adipose tissue (BAT) displays a strong circadian rhythm in metabolic activity, but it is unclear how this rhythm is regulated. As circulating levels of corticosterone coincide with the rhythm of triglyceride-derived fatty acid (FA) uptake by BAT, we investigated whether corticostero...

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Bibliographic Details
Main Authors: Jan Kroon, Maaike Schilperoort, Wietse In het Panhuis, Rosa van den Berg, Lotte van Doeselaar, Cristy R.C. Verzijl, Nikki van Trigt, Isabel M. Mol, Hetty H.C.M. Sips, Jose K. van den Heuvel, Lisa L. Koorneef, Ronald J. van der Sluis, Anna Fenzl, Florian W. Kiefer, Sabine Vettorazzi, Jan P. Tuckermann, Nienke R. Biermasz, Onno C. Meijer, Patrick C.N. Rensen, Sander Kooijman
Format: Article
Language:English
Published: Elsevier 2021-05-01
Series:Molecular Metabolism
Subjects:
Brown adipose tissue
Circadian Rhythm
Corticosterone
Glucocorticoid receptor
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877821000193

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