Phaeophytin Analogues from<em> Ligularia knorringiana</em>
A new phaeophytin, ligulariaphytin A, together with five known phaeophytins, were isolated from the aerial parts of <em>Ligularia knorringiana</em>. The structure of ligulariaphytin A was elucidated as 13<sup>1</sup>-hydroxy-13<sup&g...
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| Format: | Article |
| Language: | English |
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MDPI AG
2012-05-01
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| Series: | Molecules |
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| Online Access: | http://www.mdpi.com/1420-3049/17/5/5219 |
| _version_ | 1819212949643853824 |
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| author | Lina Li Qiusheng Zheng Qi Wang Chiaki Kuroda Hui Li |
| author_facet | Lina Li Qiusheng Zheng Qi Wang Chiaki Kuroda Hui Li |
| author_sort | Lina Li |
| collection | DOAJ |
| description | A new phaeophytin, ligulariaphytin A, together with five known phaeophytins, were isolated from the aerial parts of <em>Ligularia knorringiana</em>. The structure of ligulariaphytin A was elucidated as 13<sup>1</sup>-hydroxy-13<sup>1</sup>,13<sup>2</sup>-peroxyphaeophorbide A ethyl ester (<strong>1</strong>), and the five known compounds were identified as 13<sup>2</sup>-hydroxyphaeophorbide A ethyl ester (<strong>2</strong>), 17<sup>3</sup>-ethoxyphaeophorbide A (<strong>3</strong>), phaeophytin B (<strong>4</strong>), phaeophytin A (<strong>5</strong>), and phaeophorbide B ethyl ester (<strong>6</strong>), respectively, based on spectroscopic analysis and by comparison of their spectral data with those reported previously in the literature. All compounds were evaluated for their<em> in vitro</em> cytotoxic activities against cultured Hela cell, and were found to show only very weak cytotoxicity. |
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| id | doaj.art-1cadf8c196264021af75c8e04e003ee8 |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-12-23T06:51:06Z |
| publishDate | 2012-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-1cadf8c196264021af75c8e04e003ee82022-12-21T17:56:25ZengMDPI AGMolecules1420-30492012-05-011755219522410.3390/molecules17055219Phaeophytin Analogues from<em> Ligularia knorringiana</em>Lina LiQiusheng ZhengQi WangChiaki KurodaHui LiA new phaeophytin, ligulariaphytin A, together with five known phaeophytins, were isolated from the aerial parts of <em>Ligularia knorringiana</em>. The structure of ligulariaphytin A was elucidated as 13<sup>1</sup>-hydroxy-13<sup>1</sup>,13<sup>2</sup>-peroxyphaeophorbide A ethyl ester (<strong>1</strong>), and the five known compounds were identified as 13<sup>2</sup>-hydroxyphaeophorbide A ethyl ester (<strong>2</strong>), 17<sup>3</sup>-ethoxyphaeophorbide A (<strong>3</strong>), phaeophytin B (<strong>4</strong>), phaeophytin A (<strong>5</strong>), and phaeophorbide B ethyl ester (<strong>6</strong>), respectively, based on spectroscopic analysis and by comparison of their spectral data with those reported previously in the literature. All compounds were evaluated for their<em> in vitro</em> cytotoxic activities against cultured Hela cell, and were found to show only very weak cytotoxicity.http://www.mdpi.com/1420-3049/17/5/5219<em>Ligularia knorringiana</em>phaeophytinsligulariaphytin A |
| spellingShingle | Lina Li Qiusheng Zheng Qi Wang Chiaki Kuroda Hui Li Phaeophytin Analogues from<em> Ligularia knorringiana</em> Molecules <em>Ligularia knorringiana</em> phaeophytins ligulariaphytin A |
| title | Phaeophytin Analogues from<em> Ligularia knorringiana</em> |
| title_full | Phaeophytin Analogues from<em> Ligularia knorringiana</em> |
| title_fullStr | Phaeophytin Analogues from<em> Ligularia knorringiana</em> |
| title_full_unstemmed | Phaeophytin Analogues from<em> Ligularia knorringiana</em> |
| title_short | Phaeophytin Analogues from<em> Ligularia knorringiana</em> |
| title_sort | phaeophytin analogues from lt em gt ligularia knorringiana lt em gt |
| topic | <em>Ligularia knorringiana</em> phaeophytins ligulariaphytin A |
| url | http://www.mdpi.com/1420-3049/17/5/5219 |
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