Loss of cardiac mitochondrial complex I persulfidation impairs NAD+ homeostasis in aging

Loss of cardiac mitochondrial complex I persulfidation impairs NAD+ homeostasis in aging

Protein persulfidation is a significant post-translational modification that involves addition of a sulfur atom to the cysteine thiol group and is facilitated by sulfide species. Persulfidation targets reactive cysteine residues within proteins, influencing their structure and/or function across var...

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Bibliographic Details
Main Authors: Maria-Kyriaki Drekolia, Christina Karantanou, Ilka Wittig, Yuanyuan Li, Dominik C. Fuhrmann, Bernhard Brüne, Antonia Katsouda, Jiong Hu, Andreas Papapetropoulos, Sofia-Iris Bibli
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:Redox Biology
Subjects:
Persulfidation
Cardiac aging
CSE
3MST
NDUFB7
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231723004159

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