A long and winding road: My personal journey to oxytocin with no return

The present paper is the personal narration of the author reviewing her scientific pathways that led her toward the study of oxytocin. My work began with a pioneering study showing a decreased number of the serotonin transporter proteins in romantic lovers. This unexpected finding promoted my intere...

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Main Author: Donatella Marazziti
Format: Article
Language:English
Published: Elsevier 2023-11-01
Series:Comprehensive Psychoneuroendocrinology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666497623000322
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author Donatella Marazziti
author_facet Donatella Marazziti
author_sort Donatella Marazziti
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description The present paper is the personal narration of the author reviewing her scientific pathways that led her toward the study of oxytocin. My work began with a pioneering study showing a decreased number of the serotonin transporter proteins in romantic lovers. This unexpected finding promoted my interest in the neurobiology of human emotions and feelings, and significantly shifted my research focus from diseases to physiological states that underlie “love.” During this time increasing experimental data broadened the spectrum of activities of oxytocin from female functions, such as parturition and lactation, to modulation of the stress and immune system. The literature also began to reveal an important role for oxytocin in a sense of safety and wellbeing, processes that are critical to both love and survival. I suggest here that future studies should disentangle different emerging questions regarding the exact role of oxytocin within human nature, as well as its possible therapeutic applications in different physiological conditions and pathological states. Understanding these, in turn, holds the potential to improve the lives of both individuals and societies.
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spelling doaj.art-1cb1243b85824220bde0abedd544156d2023-12-10T06:18:04ZengElsevierComprehensive Psychoneuroendocrinology2666-49762023-11-0116100198A long and winding road: My personal journey to oxytocin with no returnDonatella Marazziti0Dipartimento di Medicina Clinica e Sperimentale, Section of Psychiatry, University of Pisa, Via Roma 67, 56100, Pisa, Italy; Saint Camillus International University of Health and Medical Sciences – UniCamillus, Rome, ItalyThe present paper is the personal narration of the author reviewing her scientific pathways that led her toward the study of oxytocin. My work began with a pioneering study showing a decreased number of the serotonin transporter proteins in romantic lovers. This unexpected finding promoted my interest in the neurobiology of human emotions and feelings, and significantly shifted my research focus from diseases to physiological states that underlie “love.” During this time increasing experimental data broadened the spectrum of activities of oxytocin from female functions, such as parturition and lactation, to modulation of the stress and immune system. The literature also began to reveal an important role for oxytocin in a sense of safety and wellbeing, processes that are critical to both love and survival. I suggest here that future studies should disentangle different emerging questions regarding the exact role of oxytocin within human nature, as well as its possible therapeutic applications in different physiological conditions and pathological states. Understanding these, in turn, holds the potential to improve the lives of both individuals and societies.http://www.sciencedirect.com/science/article/pii/S2666497623000322Personal historyBiological psychiatrySerotoninLoveOxytocin
spellingShingle Donatella Marazziti
A long and winding road: My personal journey to oxytocin with no return
Comprehensive Psychoneuroendocrinology
Personal history
Biological psychiatry
Serotonin
Love
Oxytocin
title A long and winding road: My personal journey to oxytocin with no return
title_full A long and winding road: My personal journey to oxytocin with no return
title_fullStr A long and winding road: My personal journey to oxytocin with no return
title_full_unstemmed A long and winding road: My personal journey to oxytocin with no return
title_short A long and winding road: My personal journey to oxytocin with no return
title_sort long and winding road my personal journey to oxytocin with no return
topic Personal history
Biological psychiatry
Serotonin
Love
Oxytocin
url http://www.sciencedirect.com/science/article/pii/S2666497623000322
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