Lipid Profiles of the Heads of Four Shrimp Species by UPLC–Q–Exactive Orbitrap/MS and Their Cardiovascular Activities
Lipids are key factors in nutrition, structural function, metabolic features, and other biological functions. In this study, the lipids from the heads of four species of shrimp (<i>Fenneropenaeus chinensis</i> (FC), <i>Penaeus japonicus</i> (PJ), <i>Penaeus vannamei<...
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MDPI AG
2022-01-01
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| Series: | Molecules |
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| Online Access: | https://www.mdpi.com/1420-3049/27/2/350 |
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| author | Yongqiang Zhu Peihai Li Ronghua Meng Xiaobin Li Yuezi Qiu Lizheng Wang Shanshan Zhang Xuanming Zhang Houwen Lin Hongbin Zhai Kechun Liu |
| author_facet | Yongqiang Zhu Peihai Li Ronghua Meng Xiaobin Li Yuezi Qiu Lizheng Wang Shanshan Zhang Xuanming Zhang Houwen Lin Hongbin Zhai Kechun Liu |
| author_sort | Yongqiang Zhu |
| collection | DOAJ |
| description | Lipids are key factors in nutrition, structural function, metabolic features, and other biological functions. In this study, the lipids from the heads of four species of shrimp (<i>Fenneropenaeus chinensis</i> (FC), <i>Penaeus japonicus</i> (PJ), <i>Penaeus vannamei</i> (PV), and <i>Procambarus clarkia</i> (PCC)) were compared and characterized based on UPLC–Q–Exactive Orbitrap/MS. We compared the differences in lipid composition of four kinds of shrimp head using multivariate analysis. In addition, a zebrafish model was used to evaluate pro-angiogenic, anti-inflammatory, anti-thrombotic, and cardioprotective activities of the shrimp head lipids. The lipids from the four kinds of shrimp head had different degrees of pro-angiogenic activities, and the activities of PCC and PJ shrimp lipids were more significant than those of the other two species. Four lipid groups displayed strong anti-inflammatory activities. For antithrombotic activity, only PCC (25 μg/mL) and PV (100 μg/mL) groups showed obvious activity. In terms of cardioprotective activity, the four kinds of lipid groups significantly increased the zebrafish heart rhythms. The heart distances were shortened, except for those of the FC (100 μg/mL) and PJ (25 μg/mL) groups. Our comprehensive lipidomics analysis and bioactivity study of lipids from different sources could provide a basis for the better utilization of shrimp. |
| first_indexed | 2024-03-10T00:51:35Z |
| format | Article |
| id | doaj.art-1cb1a28497964f65ba0b413c3dbb02a0 |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-03-10T00:51:35Z |
| publishDate | 2022-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-1cb1a28497964f65ba0b413c3dbb02a02023-11-23T14:50:37ZengMDPI AGMolecules1420-30492022-01-0127235010.3390/molecules27020350Lipid Profiles of the Heads of Four Shrimp Species by UPLC–Q–Exactive Orbitrap/MS and Their Cardiovascular ActivitiesYongqiang Zhu0Peihai Li1Ronghua Meng2Xiaobin Li3Yuezi Qiu4Lizheng Wang5Shanshan Zhang6Xuanming Zhang7Houwen Lin8Hongbin Zhai9Kechun Liu10Engineering Research Center of Zebrafish Models for Human Diseases and Drug Screening of Shandong Province, Key Laboratory for Biosensor of Shandong Province, Biology Institute, Qilu University of Technology, Shandong Academy of Sciences, Jinan 250103, ChinaEngineering Research Center of Zebrafish Models for Human Diseases and Drug Screening of Shandong Province, Key Laboratory for Biosensor of Shandong Province, Biology Institute, Qilu University of Technology, Shandong Academy of Sciences, Jinan 250103, ChinaPhysical and Chemical Examination Division, Zoucheng Center for Disease Control and Prevention, Zoucheng 273500, ChinaEngineering Research Center of Zebrafish Models for Human Diseases and Drug Screening of Shandong Province, Key Laboratory for Biosensor of Shandong Province, Biology Institute, Qilu University of Technology, Shandong Academy of Sciences, Jinan 250103, ChinaEngineering Research Center of Zebrafish Models for Human Diseases and Drug Screening of Shandong Province, Key Laboratory for Biosensor of Shandong Province, Biology Institute, Qilu University of Technology, Shandong Academy of Sciences, Jinan 250103, ChinaEngineering Research Center of Zebrafish Models for Human Diseases and Drug Screening of Shandong Province, Key Laboratory for Biosensor of Shandong Province, Biology Institute, Qilu University of Technology, Shandong Academy of Sciences, Jinan 250103, ChinaEngineering Research Center of Zebrafish Models for Human Diseases and Drug Screening of Shandong Province, Key Laboratory for Biosensor of Shandong Province, Biology Institute, Qilu University of Technology, Shandong Academy of Sciences, Jinan 250103, ChinaEngineering Research Center of Zebrafish Models for Human Diseases and Drug Screening of Shandong Province, Key Laboratory for Biosensor of Shandong Province, Biology Institute, Qilu University of Technology, Shandong Academy of Sciences, Jinan 250103, ChinaResearch Center for Marine Drugs, State Key Laboratory of Oncogenes and Related Genes, Department of Pharmacy, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127, ChinaKey Laboratory of Chemical Genomics, School of Chemical Biology and Biotechnology, Shenzhen Graduate School of Peking University, Shenzhen 518055, ChinaEngineering Research Center of Zebrafish Models for Human Diseases and Drug Screening of Shandong Province, Key Laboratory for Biosensor of Shandong Province, Biology Institute, Qilu University of Technology, Shandong Academy of Sciences, Jinan 250103, ChinaLipids are key factors in nutrition, structural function, metabolic features, and other biological functions. In this study, the lipids from the heads of four species of shrimp (<i>Fenneropenaeus chinensis</i> (FC), <i>Penaeus japonicus</i> (PJ), <i>Penaeus vannamei</i> (PV), and <i>Procambarus clarkia</i> (PCC)) were compared and characterized based on UPLC–Q–Exactive Orbitrap/MS. We compared the differences in lipid composition of four kinds of shrimp head using multivariate analysis. In addition, a zebrafish model was used to evaluate pro-angiogenic, anti-inflammatory, anti-thrombotic, and cardioprotective activities of the shrimp head lipids. The lipids from the four kinds of shrimp head had different degrees of pro-angiogenic activities, and the activities of PCC and PJ shrimp lipids were more significant than those of the other two species. Four lipid groups displayed strong anti-inflammatory activities. For antithrombotic activity, only PCC (25 μg/mL) and PV (100 μg/mL) groups showed obvious activity. In terms of cardioprotective activity, the four kinds of lipid groups significantly increased the zebrafish heart rhythms. The heart distances were shortened, except for those of the FC (100 μg/mL) and PJ (25 μg/mL) groups. Our comprehensive lipidomics analysis and bioactivity study of lipids from different sources could provide a basis for the better utilization of shrimp.https://www.mdpi.com/1420-3049/27/2/350lipidomicszebrafishpro-angiogenesisanti-inflammatoryantithrombosiscardioprotective |
| spellingShingle | Yongqiang Zhu Peihai Li Ronghua Meng Xiaobin Li Yuezi Qiu Lizheng Wang Shanshan Zhang Xuanming Zhang Houwen Lin Hongbin Zhai Kechun Liu Lipid Profiles of the Heads of Four Shrimp Species by UPLC–Q–Exactive Orbitrap/MS and Their Cardiovascular Activities Molecules lipidomics zebrafish pro-angiogenesis anti-inflammatory antithrombosis cardioprotective |
| title | Lipid Profiles of the Heads of Four Shrimp Species by UPLC–Q–Exactive Orbitrap/MS and Their Cardiovascular Activities |
| title_full | Lipid Profiles of the Heads of Four Shrimp Species by UPLC–Q–Exactive Orbitrap/MS and Their Cardiovascular Activities |
| title_fullStr | Lipid Profiles of the Heads of Four Shrimp Species by UPLC–Q–Exactive Orbitrap/MS and Their Cardiovascular Activities |
| title_full_unstemmed | Lipid Profiles of the Heads of Four Shrimp Species by UPLC–Q–Exactive Orbitrap/MS and Their Cardiovascular Activities |
| title_short | Lipid Profiles of the Heads of Four Shrimp Species by UPLC–Q–Exactive Orbitrap/MS and Their Cardiovascular Activities |
| title_sort | lipid profiles of the heads of four shrimp species by uplc q exactive orbitrap ms and their cardiovascular activities |
| topic | lipidomics zebrafish pro-angiogenesis anti-inflammatory antithrombosis cardioprotective |
| url | https://www.mdpi.com/1420-3049/27/2/350 |
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