Polymorphisms of Antioxidant Enzymes SOD2 (rs4880) and GPX1 (rs1050450) Are Associated with Bladder Cancer Risk or Its Aggressiveness

Polymorphisms of Antioxidant Enzymes SOD2 (rs4880) and GPX1 (rs1050450) Are Associated with Bladder Cancer Risk or Its Aggressiveness

<i>Background and Objectives</i>: Oxidative stress induced by increased reactive oxygen species (ROS) production plays an important role in carcinogenesis. The entire urinary tract is continuously exposed to numerous potentially mutagenic environmental agents which generate ROS during th...

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Bibliographic Details
Main Authors: Predrag Nikic, Dejan Dragicevic, Djurdja Jerotic, Slaviša Savic, Tatjana Djukic, Branko Stankovic, Luka Kovacevic, Tatjana Simic, Marija Matic
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Medicina
Subjects:
urothelial bladder cancer
risk
genetic polymorphisms
SNP
GPX1
SOD2
Online Access:https://www.mdpi.com/1648-9144/59/1/131

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