Soy Isoflavones Accelerate Glial Cell Migration via GPER-Mediated Signal Transduction Pathway

Soy Isoflavones Accelerate Glial Cell Migration via GPER-Mediated Signal Transduction Pathway

Soybean isoflavones, such as genistein, daidzein, and its metabolite, S-equol, are widely known as phytoestrogens. Their biological actions are thought to be exerted via the estrogen signal transduction pathway. Estrogens, such as 17β-estradiol (E2), play a crucial role in the development and functi...

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Bibliographic Details
Main Authors: Winda Ariyani, Wataru Miyazaki, Izuki Amano, Kenji Hanamura, Tomoaki Shirao, Noriyuki Koibuchi
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Endocrinology
Subjects:
genistein
daidzein
S-equol
17β-estradiol
astrocyte
F-actin
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2020.554941/full

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