Meta-analysis of risk association between interleukin-17a gene polymorphism and chronic periodontitis

The association of genetic polymorphisms with periodontitis has been studied extensively. The interleukin-7 (IL-17) is a group of cytokines, which comprises six different molecules (IL-17A, B, C, D, E, and F). Among this, IL-17A is the most commonly understood cytokine, and its polymorphism plays a...

Full description

Bibliographic Details
Main Authors: P K Sasikumar, Sheeja S Varghese, Thanga Kumaran, Sakthi Saranya Devi
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2020-01-01
Series:Contemporary Clinical Dentistry
Subjects:
Online Access:http://www.contempclindent.org/article.asp?issn=0976-237X;year=2020;volume=11;issue=1;spage=3;epage=9;aulast=Sasikumar
_version_ 1818253070087225344
author P K Sasikumar
Sheeja S Varghese
Thanga Kumaran
Sakthi Saranya Devi
author_facet P K Sasikumar
Sheeja S Varghese
Thanga Kumaran
Sakthi Saranya Devi
author_sort P K Sasikumar
collection DOAJ
description The association of genetic polymorphisms with periodontitis has been studied extensively. The interleukin-7 (IL-17) is a group of cytokines, which comprises six different molecules (IL-17A, B, C, D, E, and F). Among this, IL-17A is the most commonly understood cytokine, and its polymorphism plays a critical role in inflammatory diseases and periodontal inflammation. The present study was aimed at pooling the data available for meta-analysis and to evaluate whether IL-17A (rs2275913) polymorphism is associated with the susceptibility of chronic periodontitis.
first_indexed 2024-12-12T16:34:13Z
format Article
id doaj.art-1cb6b4639dbc417e95a921f09bf55196
institution Directory Open Access Journal
issn 0976-237X
0976-2361
language English
last_indexed 2024-12-12T16:34:13Z
publishDate 2020-01-01
publisher Wolters Kluwer Medknow Publications
record_format Article
series Contemporary Clinical Dentistry
spelling doaj.art-1cb6b4639dbc417e95a921f09bf551962022-12-22T00:18:41ZengWolters Kluwer Medknow PublicationsContemporary Clinical Dentistry0976-237X0976-23612020-01-011113910.4103/ccd.ccd_448_19Meta-analysis of risk association between interleukin-17a gene polymorphism and chronic periodontitisP K SasikumarSheeja S VargheseThanga KumaranSakthi Saranya DeviThe association of genetic polymorphisms with periodontitis has been studied extensively. The interleukin-7 (IL-17) is a group of cytokines, which comprises six different molecules (IL-17A, B, C, D, E, and F). Among this, IL-17A is the most commonly understood cytokine, and its polymorphism plays a critical role in inflammatory diseases and periodontal inflammation. The present study was aimed at pooling the data available for meta-analysis and to evaluate whether IL-17A (rs2275913) polymorphism is associated with the susceptibility of chronic periodontitis.http://www.contempclindent.org/article.asp?issn=0976-237X;year=2020;volume=11;issue=1;spage=3;epage=9;aulast=Sasikumarchronic periodontitisethnicityinterleukin-17a geneinterleukin-17a polymorphism
spellingShingle P K Sasikumar
Sheeja S Varghese
Thanga Kumaran
Sakthi Saranya Devi
Meta-analysis of risk association between interleukin-17a gene polymorphism and chronic periodontitis
Contemporary Clinical Dentistry
chronic periodontitis
ethnicity
interleukin-17a gene
interleukin-17a polymorphism
title Meta-analysis of risk association between interleukin-17a gene polymorphism and chronic periodontitis
title_full Meta-analysis of risk association between interleukin-17a gene polymorphism and chronic periodontitis
title_fullStr Meta-analysis of risk association between interleukin-17a gene polymorphism and chronic periodontitis
title_full_unstemmed Meta-analysis of risk association between interleukin-17a gene polymorphism and chronic periodontitis
title_short Meta-analysis of risk association between interleukin-17a gene polymorphism and chronic periodontitis
title_sort meta analysis of risk association between interleukin 17a gene polymorphism and chronic periodontitis
topic chronic periodontitis
ethnicity
interleukin-17a gene
interleukin-17a polymorphism
url http://www.contempclindent.org/article.asp?issn=0976-237X;year=2020;volume=11;issue=1;spage=3;epage=9;aulast=Sasikumar
work_keys_str_mv AT pksasikumar metaanalysisofriskassociationbetweeninterleukin17agenepolymorphismandchronicperiodontitis
AT sheejasvarghese metaanalysisofriskassociationbetweeninterleukin17agenepolymorphismandchronicperiodontitis
AT thangakumaran metaanalysisofriskassociationbetweeninterleukin17agenepolymorphismandchronicperiodontitis
AT sakthisaranyadevi metaanalysisofriskassociationbetweeninterleukin17agenepolymorphismandchronicperiodontitis