Meta-analysis of risk association between interleukin-17a gene polymorphism and chronic periodontitis
The association of genetic polymorphisms with periodontitis has been studied extensively. The interleukin-7 (IL-17) is a group of cytokines, which comprises six different molecules (IL-17A, B, C, D, E, and F). Among this, IL-17A is the most commonly understood cytokine, and its polymorphism plays a...
Main Authors: | , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Wolters Kluwer Medknow Publications
2020-01-01
|
Series: | Contemporary Clinical Dentistry |
Subjects: | |
Online Access: | http://www.contempclindent.org/article.asp?issn=0976-237X;year=2020;volume=11;issue=1;spage=3;epage=9;aulast=Sasikumar |
_version_ | 1818253070087225344 |
---|---|
author | P K Sasikumar Sheeja S Varghese Thanga Kumaran Sakthi Saranya Devi |
author_facet | P K Sasikumar Sheeja S Varghese Thanga Kumaran Sakthi Saranya Devi |
author_sort | P K Sasikumar |
collection | DOAJ |
description | The association of genetic polymorphisms with periodontitis has been studied extensively. The interleukin-7 (IL-17) is a group of cytokines, which comprises six different molecules (IL-17A, B, C, D, E, and F). Among this, IL-17A is the most commonly understood cytokine, and its polymorphism plays a critical role in inflammatory diseases and periodontal inflammation. The present study was aimed at pooling the data available for meta-analysis and to evaluate whether IL-17A (rs2275913) polymorphism is associated with the susceptibility of chronic periodontitis. |
first_indexed | 2024-12-12T16:34:13Z |
format | Article |
id | doaj.art-1cb6b4639dbc417e95a921f09bf55196 |
institution | Directory Open Access Journal |
issn | 0976-237X 0976-2361 |
language | English |
last_indexed | 2024-12-12T16:34:13Z |
publishDate | 2020-01-01 |
publisher | Wolters Kluwer Medknow Publications |
record_format | Article |
series | Contemporary Clinical Dentistry |
spelling | doaj.art-1cb6b4639dbc417e95a921f09bf551962022-12-22T00:18:41ZengWolters Kluwer Medknow PublicationsContemporary Clinical Dentistry0976-237X0976-23612020-01-011113910.4103/ccd.ccd_448_19Meta-analysis of risk association between interleukin-17a gene polymorphism and chronic periodontitisP K SasikumarSheeja S VargheseThanga KumaranSakthi Saranya DeviThe association of genetic polymorphisms with periodontitis has been studied extensively. The interleukin-7 (IL-17) is a group of cytokines, which comprises six different molecules (IL-17A, B, C, D, E, and F). Among this, IL-17A is the most commonly understood cytokine, and its polymorphism plays a critical role in inflammatory diseases and periodontal inflammation. The present study was aimed at pooling the data available for meta-analysis and to evaluate whether IL-17A (rs2275913) polymorphism is associated with the susceptibility of chronic periodontitis.http://www.contempclindent.org/article.asp?issn=0976-237X;year=2020;volume=11;issue=1;spage=3;epage=9;aulast=Sasikumarchronic periodontitisethnicityinterleukin-17a geneinterleukin-17a polymorphism |
spellingShingle | P K Sasikumar Sheeja S Varghese Thanga Kumaran Sakthi Saranya Devi Meta-analysis of risk association between interleukin-17a gene polymorphism and chronic periodontitis Contemporary Clinical Dentistry chronic periodontitis ethnicity interleukin-17a gene interleukin-17a polymorphism |
title | Meta-analysis of risk association between interleukin-17a gene polymorphism and chronic periodontitis |
title_full | Meta-analysis of risk association between interleukin-17a gene polymorphism and chronic periodontitis |
title_fullStr | Meta-analysis of risk association between interleukin-17a gene polymorphism and chronic periodontitis |
title_full_unstemmed | Meta-analysis of risk association between interleukin-17a gene polymorphism and chronic periodontitis |
title_short | Meta-analysis of risk association between interleukin-17a gene polymorphism and chronic periodontitis |
title_sort | meta analysis of risk association between interleukin 17a gene polymorphism and chronic periodontitis |
topic | chronic periodontitis ethnicity interleukin-17a gene interleukin-17a polymorphism |
url | http://www.contempclindent.org/article.asp?issn=0976-237X;year=2020;volume=11;issue=1;spage=3;epage=9;aulast=Sasikumar |
work_keys_str_mv | AT pksasikumar metaanalysisofriskassociationbetweeninterleukin17agenepolymorphismandchronicperiodontitis AT sheejasvarghese metaanalysisofriskassociationbetweeninterleukin17agenepolymorphismandchronicperiodontitis AT thangakumaran metaanalysisofriskassociationbetweeninterleukin17agenepolymorphismandchronicperiodontitis AT sakthisaranyadevi metaanalysisofriskassociationbetweeninterleukin17agenepolymorphismandchronicperiodontitis |