Nanoporous Silicified Phospholipids and Application to Controlled Glycolic Acid Release
<p>Abstract</p> <p>This work demonstrates the synthesis and characterization of novel nanoporous silicified phospholipid bilayers assembled inorganic powders. The materials are obtained by silicification process with silica precursor at the hydrophilic region of phospholipid bilaye...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
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SpringerOpen
2008-01-01
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Series: | Nanoscale Research Letters |
Subjects: | |
Online Access: | http://dx.doi.org/10.1007/s11671-008-9165-x |
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author | Kang SangHwa Lee HyeSun Lee Jiho Jeong Seongmin Choi Jinsub Lee SangCheon Kim KyungJa Chang JeongHo |
author_facet | Kang SangHwa Lee HyeSun Lee Jiho Jeong Seongmin Choi Jinsub Lee SangCheon Kim KyungJa Chang JeongHo |
author_sort | Kang SangHwa |
collection | DOAJ |
description | <p>Abstract</p> <p>This work demonstrates the synthesis and characterization of novel nanoporous silicified phospholipid bilayers assembled inorganic powders. The materials are obtained by silicification process with silica precursor at the hydrophilic region of phospholipid bilayers. This process involves the co-assembly of a chemically active phospholipids bilayer within the ordered porosity of a silica matrix and holds promise as a novel application for controlled drug release or drug containers with a high level of specificity and throughput. The controlled release application of the synthesized materials was achieved to glycolic acid, and obtained a zero-order release pattern due to the nanoporosity.</p> |
first_indexed | 2024-03-12T19:40:03Z |
format | Article |
id | doaj.art-1cb763d83af94b0286bcb635a4a87786 |
institution | Directory Open Access Journal |
issn | 1931-7573 1556-276X |
language | English |
last_indexed | 2024-03-12T19:40:03Z |
publishDate | 2008-01-01 |
publisher | SpringerOpen |
record_format | Article |
series | Nanoscale Research Letters |
spelling | doaj.art-1cb763d83af94b0286bcb635a4a877862023-08-02T03:51:54ZengSpringerOpenNanoscale Research Letters1931-75731556-276X2008-01-01310355360Nanoporous Silicified Phospholipids and Application to Controlled Glycolic Acid ReleaseKang SangHwaLee HyeSunLee JihoJeong SeongminChoi JinsubLee SangCheonKim KyungJaChang JeongHo<p>Abstract</p> <p>This work demonstrates the synthesis and characterization of novel nanoporous silicified phospholipid bilayers assembled inorganic powders. The materials are obtained by silicification process with silica precursor at the hydrophilic region of phospholipid bilayers. This process involves the co-assembly of a chemically active phospholipids bilayer within the ordered porosity of a silica matrix and holds promise as a novel application for controlled drug release or drug containers with a high level of specificity and throughput. The controlled release application of the synthesized materials was achieved to glycolic acid, and obtained a zero-order release pattern due to the nanoporosity.</p>http://dx.doi.org/10.1007/s11671-008-9165-xNanoporousPhospholipidsSilicificationSol–gelControlled releaseGlycolic acid |
spellingShingle | Kang SangHwa Lee HyeSun Lee Jiho Jeong Seongmin Choi Jinsub Lee SangCheon Kim KyungJa Chang JeongHo Nanoporous Silicified Phospholipids and Application to Controlled Glycolic Acid Release Nanoscale Research Letters Nanoporous Phospholipids Silicification Sol–gel Controlled release Glycolic acid |
title | Nanoporous Silicified Phospholipids and Application to Controlled Glycolic Acid Release |
title_full | Nanoporous Silicified Phospholipids and Application to Controlled Glycolic Acid Release |
title_fullStr | Nanoporous Silicified Phospholipids and Application to Controlled Glycolic Acid Release |
title_full_unstemmed | Nanoporous Silicified Phospholipids and Application to Controlled Glycolic Acid Release |
title_short | Nanoporous Silicified Phospholipids and Application to Controlled Glycolic Acid Release |
title_sort | nanoporous silicified phospholipids and application to controlled glycolic acid release |
topic | Nanoporous Phospholipids Silicification Sol–gel Controlled release Glycolic acid |
url | http://dx.doi.org/10.1007/s11671-008-9165-x |
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