Nanoporous Silicified Phospholipids and Application to Controlled Glycolic Acid Release

<p>Abstract</p> <p>This work demonstrates the synthesis and characterization of novel nanoporous silicified phospholipid bilayers assembled inorganic powders. The materials are obtained by silicification process with silica precursor at the hydrophilic region of phospholipid bilaye...

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Main Authors: Kang SangHwa, Lee HyeSun, Lee Jiho, Jeong Seongmin, Choi Jinsub, Lee SangCheon, Kim KyungJa, Chang JeongHo
Format: Article
Language:English
Published: SpringerOpen 2008-01-01
Series:Nanoscale Research Letters
Subjects:
Online Access:http://dx.doi.org/10.1007/s11671-008-9165-x
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author Kang SangHwa
Lee HyeSun
Lee Jiho
Jeong Seongmin
Choi Jinsub
Lee SangCheon
Kim KyungJa
Chang JeongHo
author_facet Kang SangHwa
Lee HyeSun
Lee Jiho
Jeong Seongmin
Choi Jinsub
Lee SangCheon
Kim KyungJa
Chang JeongHo
author_sort Kang SangHwa
collection DOAJ
description <p>Abstract</p> <p>This work demonstrates the synthesis and characterization of novel nanoporous silicified phospholipid bilayers assembled inorganic powders. The materials are obtained by silicification process with silica precursor at the hydrophilic region of phospholipid bilayers. This process involves the co-assembly of a chemically active phospholipids bilayer within the ordered porosity of a silica matrix and holds promise as a novel application for controlled drug release or drug containers with a high level of specificity and throughput. The controlled release application of the synthesized materials was achieved to glycolic acid, and obtained a zero-order release pattern due to the nanoporosity.</p>
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spelling doaj.art-1cb763d83af94b0286bcb635a4a877862023-08-02T03:51:54ZengSpringerOpenNanoscale Research Letters1931-75731556-276X2008-01-01310355360Nanoporous Silicified Phospholipids and Application to Controlled Glycolic Acid ReleaseKang SangHwaLee HyeSunLee JihoJeong SeongminChoi JinsubLee SangCheonKim KyungJaChang JeongHo<p>Abstract</p> <p>This work demonstrates the synthesis and characterization of novel nanoporous silicified phospholipid bilayers assembled inorganic powders. The materials are obtained by silicification process with silica precursor at the hydrophilic region of phospholipid bilayers. This process involves the co-assembly of a chemically active phospholipids bilayer within the ordered porosity of a silica matrix and holds promise as a novel application for controlled drug release or drug containers with a high level of specificity and throughput. The controlled release application of the synthesized materials was achieved to glycolic acid, and obtained a zero-order release pattern due to the nanoporosity.</p>http://dx.doi.org/10.1007/s11671-008-9165-xNanoporousPhospholipidsSilicificationSol&#8211;gelControlled releaseGlycolic acid
spellingShingle Kang SangHwa
Lee HyeSun
Lee Jiho
Jeong Seongmin
Choi Jinsub
Lee SangCheon
Kim KyungJa
Chang JeongHo
Nanoporous Silicified Phospholipids and Application to Controlled Glycolic Acid Release
Nanoscale Research Letters
Nanoporous
Phospholipids
Silicification
Sol&#8211;gel
Controlled release
Glycolic acid
title Nanoporous Silicified Phospholipids and Application to Controlled Glycolic Acid Release
title_full Nanoporous Silicified Phospholipids and Application to Controlled Glycolic Acid Release
title_fullStr Nanoporous Silicified Phospholipids and Application to Controlled Glycolic Acid Release
title_full_unstemmed Nanoporous Silicified Phospholipids and Application to Controlled Glycolic Acid Release
title_short Nanoporous Silicified Phospholipids and Application to Controlled Glycolic Acid Release
title_sort nanoporous silicified phospholipids and application to controlled glycolic acid release
topic Nanoporous
Phospholipids
Silicification
Sol&#8211;gel
Controlled release
Glycolic acid
url http://dx.doi.org/10.1007/s11671-008-9165-x
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