The Enhanced metastatic potential of hepatocellular carcinoma (HCC) cells with sorafenib resistance.

Acquired resistance towards sorafenib treatment was found in HCC patients, which results in poor prognosis. To investigate the enhanced metastatic potential of sorafenib resistance cells, sorafenib-resistant (SorR) cell lines were established by long-term exposure of the HCC cells to the maximum tol...

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Bibliographic Details
Main Authors: Ariel Ka-Man Chow, Lui Ng, Colin Siu-Chi Lam, Sunny Kit-Man Wong, Timothy Ming-Hun Wan, Nathan Shiu-Man Cheng, Thomas Chung-Cheung Yau, Ronnie Tung-Ping Poon, Roberta Wen-Chi Pang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3823841?pdf=render