Complex cytogenetic abnormalities in chronic myeloid leukemia resulting in early progression to blast crisis: a case report

Abstract Introduction BCR-ABL1, resulting from t(9;22), is the oncogenic driver of chronic myeloid leukemia and the therapeutic target of the disease. Molecular studies have been the gold standard modality for patient assessment since the advent of tyrosine kinase inhibitor therapy. In spite of that...

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Главные авторы: Haider Ali Malakzai, Soma Rahmani, Ahmed Maseh Haidary, Sarah Noor, Maryam Ahmad, Abdul Sami Ibrahimkhil, Samuel Sharif
Формат: Статья
Язык:English
Опубликовано: BMC 2020-11-01
Серии:Journal of Medical Case Reports
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Online-ссылка:https://doi.org/10.1186/s13256-020-02539-x