Effectiveness and safety research of Qingfei Paidu (QFPD) in treatment of COVID-19: an up-to-date systematic review and meta-analysis
Abstract Background Since the outbreak of COVID-19 in 2019, the global economy, culture, politics, and people's lives and health have been severely damaged and threatened. Although western modern medical treatment has made great efforts, the treatment of COVID-19 has not achieved ideal clinical...
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| Format: | Article |
| Language: | English |
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BMC
2022-10-01
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| Series: | Chinese Medicine |
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| Online Access: | https://doi.org/10.1186/s13020-022-00675-8 |
| _version_ | 1811257115714519040 |
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| author | Xinxin Wang Tao Ma Wei Zhang Qiang Chu |
| author_facet | Xinxin Wang Tao Ma Wei Zhang Qiang Chu |
| author_sort | Xinxin Wang |
| collection | DOAJ |
| description | Abstract Background Since the outbreak of COVID-19 in 2019, the global economy, culture, politics, and people's lives and health have been severely damaged and threatened. Although western modern medical treatment has made great efforts, the treatment of COVID-19 has not achieved ideal clinical efficacy with severe sequelae. Qingfei Paidu (QFPD), an important herbal prescription for COVID-19 treatment, has shown remarkable therapeutic effects in China's fight against the epidemic. Materials and methods We searched seven databases up to 7 September 2022, including PubMed, Chinese National Knowledge Infrastructure (CNKI), Wanfang Database, Cochrane Central Register of Controlled Trials (CENTRAL), EMBASE, World Scientific and SpringerLink. We used the Cochrane Risk of Bias tool to assess the quality of randomized controlled trials. All analysis results were conducted by RevMan 5.4.1 to carry out a meta-analysis. Results Fifteen studies with 10390 patients were included. QFPD could not only significantly improve the cure rate and lung CT of COVID-19, reduce the number of patients turning to critical condition and death, shorten the time for nucleic acid conversion and the length of hospital stay, but change laboratory indexes and relieve body symptoms quickly without adverse effects. Conclusions Compared with patients only treated by conventional western treatment (CWM), QFPD combined with CWM could be more effective for patients. It is worth spreading to other countries in the global battle against COVID-19. |
| first_indexed | 2024-04-12T17:51:32Z |
| format | Article |
| id | doaj.art-1cbd80b6f83241b8b10382c438b43998 |
| institution | Directory Open Access Journal |
| issn | 1749-8546 |
| language | English |
| last_indexed | 2024-04-12T17:51:32Z |
| publishDate | 2022-10-01 |
| publisher | BMC |
| record_format | Article |
| series | Chinese Medicine |
| spelling | doaj.art-1cbd80b6f83241b8b10382c438b439982022-12-22T03:22:29ZengBMCChinese Medicine1749-85462022-10-0117111610.1186/s13020-022-00675-8Effectiveness and safety research of Qingfei Paidu (QFPD) in treatment of COVID-19: an up-to-date systematic review and meta-analysisXinxin Wang0Tao Ma1Wei Zhang2Qiang Chu3Jinling Institute of TechnologyDepartment of Traditional Chinese Medicine, Gusheng Tang Stone Road ClinicXinyi People’s HospitalKowloon HospitalAbstract Background Since the outbreak of COVID-19 in 2019, the global economy, culture, politics, and people's lives and health have been severely damaged and threatened. Although western modern medical treatment has made great efforts, the treatment of COVID-19 has not achieved ideal clinical efficacy with severe sequelae. Qingfei Paidu (QFPD), an important herbal prescription for COVID-19 treatment, has shown remarkable therapeutic effects in China's fight against the epidemic. Materials and methods We searched seven databases up to 7 September 2022, including PubMed, Chinese National Knowledge Infrastructure (CNKI), Wanfang Database, Cochrane Central Register of Controlled Trials (CENTRAL), EMBASE, World Scientific and SpringerLink. We used the Cochrane Risk of Bias tool to assess the quality of randomized controlled trials. All analysis results were conducted by RevMan 5.4.1 to carry out a meta-analysis. Results Fifteen studies with 10390 patients were included. QFPD could not only significantly improve the cure rate and lung CT of COVID-19, reduce the number of patients turning to critical condition and death, shorten the time for nucleic acid conversion and the length of hospital stay, but change laboratory indexes and relieve body symptoms quickly without adverse effects. Conclusions Compared with patients only treated by conventional western treatment (CWM), QFPD combined with CWM could be more effective for patients. It is worth spreading to other countries in the global battle against COVID-19.https://doi.org/10.1186/s13020-022-00675-8COVID-19Effective treatment options for COVID-19Traditional Chinese medicine(TCM)Qingfei PaiduRandomized controlled trialSystematic review |
| spellingShingle | Xinxin Wang Tao Ma Wei Zhang Qiang Chu Effectiveness and safety research of Qingfei Paidu (QFPD) in treatment of COVID-19: an up-to-date systematic review and meta-analysis Chinese Medicine COVID-19 Effective treatment options for COVID-19 Traditional Chinese medicine(TCM) Qingfei Paidu Randomized controlled trial Systematic review |
| title | Effectiveness and safety research of Qingfei Paidu (QFPD) in treatment of COVID-19: an up-to-date systematic review and meta-analysis |
| title_full | Effectiveness and safety research of Qingfei Paidu (QFPD) in treatment of COVID-19: an up-to-date systematic review and meta-analysis |
| title_fullStr | Effectiveness and safety research of Qingfei Paidu (QFPD) in treatment of COVID-19: an up-to-date systematic review and meta-analysis |
| title_full_unstemmed | Effectiveness and safety research of Qingfei Paidu (QFPD) in treatment of COVID-19: an up-to-date systematic review and meta-analysis |
| title_short | Effectiveness and safety research of Qingfei Paidu (QFPD) in treatment of COVID-19: an up-to-date systematic review and meta-analysis |
| title_sort | effectiveness and safety research of qingfei paidu qfpd in treatment of covid 19 an up to date systematic review and meta analysis |
| topic | COVID-19 Effective treatment options for COVID-19 Traditional Chinese medicine(TCM) Qingfei Paidu Randomized controlled trial Systematic review |
| url | https://doi.org/10.1186/s13020-022-00675-8 |
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